Molecular Mechanisms of Cardiac Hypertrophy and Failure.
General Material Designation
[Book]
First Statement of Responsibility
Richard A Walsh
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
London
Name of Publisher, Distributor, etc.
Informa Healthcare
Date of Publication, Distribution, etc.
2005
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
(1038 pages)
CONTENTS NOTE
Text of Note
Book Cover; Half-Title; Title; Copyright; Dedication; Contents; Contributors; Preface; Acknowledgements; Abbreviations; Color Plate Section; Section I Mechanisms for Cardiac Hypertrophy; 1. Mechanisms of Normal Cardiovascular Growth and Development; 2. Cardiomyocyte Cell Cycle Control; 3. Molecular Mechanisms of Cardiac Myocyte Death; 4. Transcription Factors and Hypertrophy; 5. G Protein-coupled Receptor Activation; 6. Mechanotransduction in Cardiomyocyte Hypertrophy; 7. Extracellular Matrix; 8. Physiological Versus Pathological Cardiac Hypertrophy; 9. Alterations in Signal Transduction. 10. Cell-based Therapies for Cardiac Regeneration and Repair11. Oxidative Stress in the Regulation of Myocardial Hypertrophy and Failure; Section II Mechanisms for Contractile Depression; 12. Normal and Abnormal Excitation-contraction Coupling; 13. Normal and Abnormal Calcium Homeostasis; 14. Mechanisms of Reversible Ischemic Dysfunction; 15. Cardiac Remodeling; 16. The Role of Inflammatory Mediators in Cardiac Hypertrophy, C.
SUMMARY OR ABSTRACT
Text of Note
The major impetus for the design and execution of Molecular Mechanisms for CardiacHypertrophy and Failure has been the remarkable insights into the pathogenesis ofabnormal cardiac growth and function that have been derived from the application ofmolecular and cellular approaches to this problem over the past decade. The syndrome ofcongestive heart failure is a major and growing public health problem in both developedand developing countries. In developed countries, the aging of our populations hasallowed more protracted impacts of genetic and environmental factors that have resultedin the cont.