Intrinsic mutagenesis, a genetic approach to ageing
General Material Designation
[Book]
First Statement of Responsibility
Sir Macfarlane Burnet.
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
New York
Name of Publisher, Distributor, etc.
J. Wiley
Date of Publication, Distribution, etc.
[1974]
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
ix, 244 pages : graphs ; 23 cm.
SERIES
Series Title
Wiley biomedical-health publication.
CONTENTS NOTE
Text of Note
Part 1: Mutation and the concept of intrinsic mutagenesis --;1. The two imperatives --;2. Intrinsic mutagenesis: an elementary discussion at the level of molecular biology --;3. Mutator genes and other leads from bacterial genetics --;4. Mutation in evolution --;5. Somatic mutations --;Part 2: Physiology and pathology of ageing --;6. The manifestations of ageing --;7. Ageing: the somatic mutational approach --;8. The thymus in relation to ageing --;9. Other immunological aspects in ageing --;10. Atherosclerosis --;11. Hypothesis of the genetic control of lifespan --;Part 3: Malignant disease --;12. Malignant disease (1) --;13. Malignant disease (2) --;14. Immune surveillance --;15. Lymphoreticular malignancies and their relation to herpesvirus infections --;Part 4: Other age-associated conditions --;16. Human congenital anomalies --;17. Normal and pathological ageing in the post-mitotic cells of the brain --;18. Social implications of the biological approach to ageing.