عنوان

Ocular transporters and receptors :

(Number (ISBN

1907568867

(Number (ISBN

9781907568862

Number

b542689

Title Proper

Ocular transporters and receptors :

General Material Designation

[Book]

Other Title Information

their role in drug delivery

First Statement of Responsibility

edited by Ashim K. Mitra

Place of Publication, Distribution, etc.

Oxford

Name of Publisher, Distributor, etc.

WP, Woodhead Publishing

Date of Publication, Distribution, etc.

2013

Specific Material Designation and Extent of Item

xxiii, 251 pages : illustrations ; 25 cm

Series Title

Woodhead Publishing series in biomedicine, no. 39

Text of Note

List of figures and tables About the authors Chapter 1: Eye: anatomy, physiology and barriers to drug delivery Abstract: 1.1 Introduction 1.2 Anatomy and physiology of the eye 1.3 Barriers to ocular drug delivery 1.4 Conclusions 1.5 Acknowledgements Chapter 2: Biology of ocular transporters: efflux and influx transporters in the eye Abstract: 2.1 Introduction 2.2 SLC transporters 2.3 ABC transporters 2.4 Conclusions Chapter 3: Characterization of ocular transporters Abstract: 3.1 Introduction 3.2 Molecular and cellular characterization 3.3 Functional characterization of transporters Chapter 4: Transporters and receptors in the anterior segment of the eye Abstract: 4.1 Introduction 4.2 Transporters and receptors 4.3 Anterior chamber influx transporters 4.4 Anterior chamber efflux transporters 4.5 Anterior chamber receptors 4.6 Other miscellaneous anterior chamber receptors 4.7 Conclusions Chapter 5: Transporters and receptors in the posterior segment of the eye Abstract: 5.1 Introduction 5.2 Influx transporters in posterior segment of the eye 5.3 Receptors in posterior segment of the eye 5.4 ABC transporters 5.5 Conclusion Chapter 6: Transporters in drug discovery and delivery: a new paradigm in ocular drug design Abstract: 6.1 Introduction 6.2 Transporter-targeted drug delivery to the anterior segment 6.3 Transporter-targeted drug delivery to the posterior segment 6.4 Conclusion Chapter 7: Transporter-metabolism interplay in the eye Abstract: 7.1 Introduction 7.2 Metabolizing enzymes in ocular tissues 7.3 Impact of disease state on the expression of metabolizing enzymes 7.4 Efflux transporters and metabolism interplay 7.5 Potential impact of the efflux metabolism interplay in ocular bioavailability 7.6 Drug design and formulation strategies to overcome the efflux and metabolism interplay 7.7 Conclusion Index

Biological transport.

Drug targeting.

Eye -- Physiology.

Class number

Book number

edited by Ashim K. Mitra

Ashim K Mitra

Electronic name

[Book]

Y