The Use and Misuse of Sleeping Pills A Clinical Guide.
General Material Designation
[Book]
First Statement of Responsibility
Mendelson, Wallace B.
.PUBLICATION, DISTRIBUTION, ETC
Name of Publisher, Distributor, etc.
Springer Verlag
Date of Publication, Distribution, etc.
2012
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
pages
CONTENTS NOTE
Text of Note
1 Basic Concepts about Sleep and Insomnia.- History.- The Sleep Stages.- Waking.- NonREM Sleep.- Stage 1.- Stage 2.- Stages 3 and 4.- REM Sleep.- Influences on the Appearance of Sleep Stages.- Physiologic Regulation of Sleep.- Passive versus Active Model.- The Neurotransmitters.- Circulating Humors.- Hypnotics and Sleep Regulation.- Sleep Deprivation.- The Need for Sleep.- Insomnia.- Summary and Conclusions.- 2 The Prevalence of Sleep Disturbance and Hypnotic Use.- Surveys of Reported Sleep Disturbance.- Types of Sleep Complaints.- Surveys of Hypnotic Use.- Patient-Physician Interaction.- Prescriptions for Outpatients.- Prescribing Hypnotics in Hospital Practice.- Summary and Conclusions.- 3 Pharmacology of Prescription Hypnotics.- Pharmacologic Considerations.- Barbiturates.- History.- Actions.- Structure and Classification.- Alterations in Metabolism and Excretion: Illness, Old Age, Enzyme Induction.- Chronic Administration.- Benzodiazepines.- History.- Flurazepam.- Nitrazepam.- Temazepam.- Other Properties of Benzodiazepines.- Nonbarbiturate, Nonbenzodiazepine Hypnotics.- Chloral Hydrate and Derivatives.- Methaqualone.- Piperidinedione Derivatives.- Glutethimide.- Methyprylonz.- Ethchlorvynol.- Ethinamate.- Summary and Conclusions.- 4 The Efficacy of Hypnotics.- Methodologic Considerations.- Possible Measures of Efficacy.- Subject Selection.- Other Methodological Issues.- Efficacy Studies in Specific Disorders.- Reference Section: Efficacy Studies in Normal Volunteers and "Insomniacs".- Barbiturates.- Benzodiazepines.- Flurazepam.- Nitrazepam.- Temazepam.- Nonbarbiturate, Nonbenzodiazepine Hypnotics.- Chloral Hydrate.- Methaqualone.- Glutethimide.- Methyprylon.- Ethchlorvynol.- Summary and Conclusions.- 5 Suicide and Hypnotics.- Incidence.- Traits of the Victim.- Clinical Toxicity.- Barbiturates.- Benzodiazepines.- Nonbarbiturate, Nonbenzodiazepine Hypnotics.- ChloralHydrate.- Methaqualone.- Glutethimide.- Ethchlorvynol.- Treatment.- Prevention.- Summary and Conclusions.- 6 Residual Daytime Effects of Hypnotics.- Electrophysiologic Residual Effects.- Psychomotor Measures of Residual Effects.- Subjective Evaluation of Daytime Performance.- Hypnotics and Driving.- Summary and Conclusions.- 7 Interactions with Ethanol.- General Considerations.- Barbiturates.- Benzodiazepines.- Nonbarbiturate, Nonbenzodiazepine Hypnotics.- Chloral Hydrate.- Methaqualone.- Glutethimide.- Summary and Conclusions.- 8 Hypnotic Dependence.- Classical Drug Abuse.- Dependence in Medical Practice.- Dependence on Extremely Large Doses.- Prolonged Use of Recommended Doses.- Incidence and Contributing Factors.- Drug Qualities Related to Prolonged Use.- Summary and Conclusions.- 9 Hypnotics and the Elderly.- Pharmacology in the Elderly.- Efficacy Studies.- Toxicity.- Summary and Conclusions.- 10 Other Pharmacologic Approaches.- Over-the-Counter Hypnotics.- Compounds Used in OTC Hypnotics.- Methapyrilene.- Scopolamine.- Bromides.- Efficacy.- Federal Regulation.- l-Tryptophan.- Ethanol.- Summary and Conclusions.- 11 Nonpharmacologic Treatment of Insomnia.- Counseling and Psychotherapy.- Behavioral Therapies.- General Considerations.- Relaxation Procedures.- Conditioning-Derived Therapies.- Attributional Therapy.- Behavioral Self-Management.- Summary and Conclusions.- 12 Conclusion: Implications for Medical Practice.- Summary.- Approach to the Insomniac Patient.- Evaluation.- The Decision Whether to Give Hypnotics.- Acute or Intermittent Insomnia.- Chronic Insomnia.- When Hypnotics Are Prescribed.- References.