عنوان

New Concepts in Viral Heart Disease Virology, Immunology and Clinical Management

(Number (ISBN

3642736122

(Number (ISBN

9783642736124

Number

b539619

Title Proper

New Concepts in Viral Heart Disease Virology, Immunology and Clinical Management

General Material Designation

[Book]

First Statement of Responsibility

H P Schultheiß

Edition Statement

Softcover reprint of the original 1st ed. 1988

Name of Publisher, Distributor, etc.

Berlin Springer Berlin

Date of Publication, Distribution, etc.

2013

Specific Material Designation and Extent of Item

XI, 504 Seiten in 1 Teil XI, 504 Seiten, 140 schw.-w. Illustrationen, 16 farbige Illustrationen, 58 schw.-w. Tabellen 244 x 170 mm

Text of Note

I. Epidemiology and Natural History.- The Etiology, Pathogenesis and Pathophysiology of Dilated Cardiomyopathies.- Virological, Immunological and Clinical Features of Myocarditis and Dilated Cardiomyopathy.- Epidemiology and Pathogenicity of Coxsackieviruses.- Natural History of Acute Viral or Idiopathic Myocarditis: A Clinical and Endomycardial Biopsy Follow-up.- Myocarditis in Patients with Dilated Cardiomyopathy- Correlation with Clinical, Hemodynamic and Biochemical Findings.- Coxsackievirus Cardiomyopathy in Animal Models, Including the Augmenting Effect of Exercise During the Acute Phase.- II. Concepts in Viral Pathogenesis.- Replication, Molecular Biology, and Pathogenesis of Coxsackieviruses.- A Murine Model for Coxsackievirus B3-Induced Acute Myocardial Necrosis for Study of Cellular Receptors as Determinants of Viral Tropism.- Induction of Soluble Mediators During Coxsackievirus B3 Replication In Vitro and In Vivo.- Persistence of Echovirus Type 6 in Cultured Cells.- Detection and Typing of Enteroviruses by Nucleic Acid Probes and Monoclonal Antibodies.- Generation of Enterovirus Group-Specific Antisera Using Bacterially Synthesized Coxsackievirus B3 Proteins.- III. Virus and Immunity.- Myocarditis: A Post-infectious Autoimmune Disease.- Viral Myocarditis: Immunogenetic and Autoimmune Aspects.- Is Coxsackievirus B3-Induced Myocarditis in A/J Mice Mediated by an Autoimmune Response to Cardiac Myosin?.- Virus-Induced Autoimmunity: Cross-Reactivity of Antiviral Antibodies with Self-Components.- Immunopathogenic Mechanisms in Experimental Myocarditis: Evidence for Autoimmunity to the Virus Receptor and Antigenic Mimicry Between the Virus and Cardiocyte.- Coxsackie B3 Myocarditis: Genetic Aspects of Different Immunopathogenetic Mechanisms in BALB/c and DBA/2 Mice. Antigenic Specificity of Heart-Reactive Antibodies in DBA/2 Mice.- Interactions of Group B Coxsackieviruses with Immunocytes.- Early Cellular Infiltrates in Coxsackievirus B3 Murine Myocarditis.- IV. Characterization of Autoimmunological Mechanisms.- Beta-Adrenoceptor Autoantibodies in Idiopathic Dilated Cardiomyopathy.- Antibodies Against the ADP/ATP Carrier Crossreact with the Ca-Channel - Functional and Biochemical Data.- Antibodies and Autoantibodies against ADP/ATP Carrier Enhance Calcium Current in Isolated Ventricular Myocytes.- Antibodies Against the ADP/ATP Carrier Alter Myocardial Function by Disturbing Cellular Energy Metabolism.- The Importance of Humoral and Cellular Immunological Parameters for the Pathogenesis of Viral Myocarditis.- Characterization of T-Lymphocytes Cultured from Human Endomyocardial Biopsies.- V. Diagnostic Criteria.- The Role of Biopsy in the Diagnosis and Follow-up of Myocarditis. A Critical Review.- Impaired Myocardial Ultra-Structure and Cytoskeleton in Cardiomyopathic Human Myocardium.- Immunofluorescence Microscopy in the Diagnosis and Follow-up of Patients Suspected of Having Inflammatory Heart Disease.- of Major Histocompatibility (MHC) Antigens on Myocardial Cells in Patients with Active Myocarditis and Idiopathic Cardiomyopathy.- Evalution of Immunohistological Data for the Diagnosis of Myocarditis.- Enteroviral Heart Disease: Diagnosis by In Situ Hybridization.- Persistence of Enterovirus RNA in Dilated Cardiomyopathy: A Progression from Myocarditis.- Diagnosis of Acute Myocarditis with Radiolabeled Monoclonal Antimyosin Antibody: Immunoscintigraphic Evaluation.- VI. Immuno-Modulating Therapy: Experimental and Clinical Approaches.- Animal Models for Therapeutic Trials of Viral Myocarditis: Effect of Ribavirin and Alpha Interferon on Coxsackievirus B3 and Encephalomyocarditis Virus Myocarditis.- Antiviral Activity of Human Fibroblast Interferon in Coxsackievirus B3-Infected Cultured Human Heart Cells.- Immunosuppressive Therapy in Myocarditis: Acute Viral Versus Chronic Idiopathic Myocarditis.- Immunosuppressive Treatment in Myocarditis.- The Role of Cardiac Transplantation in Patients with Active Myocarditis.- Clinical and Experimental Aspects of Treatment for Viral Myocarditis.- VII. New Aspects of Clinical Management.- Alterations of Receptors and of Agonist Effectiveness in Myocardial Failure.- Positive Inotropic Drugs in the Treatment of Chronic Congestive Heart Failure: A Critical Up-date.- Effect of ACE-Inhibitors on Myocardial Perfusion.- Experimental Evidence for Cardioprotection Afforded by Ramipril, an Inhibitor of Angiotensin Converting Enzyme.- Energetic Consequences of Pharmacological Therapy in Patients with Myocardial Failure.- The Effect of ACE Inhibitors on Energy Metabolism in Chronic Heart Failure - Enzymatic Studies of Myocardial Biopsies.

Class number

Book number

H P Schultheiß

H P Schultheiß

Electronic name

[Book]

Y