عنوان

Hereditary Diseases and Blood Transfusion Proceedings of the Nineteenth International Symposium on Blood Transfusion, Groningen 1994, Organized by the Red Cross Blood Bank Groningen-drenthe.

(Number (ISBN

1461358345

(Number (ISBN

9781461358343

Number

b537195

Title Proper

Hereditary Diseases and Blood Transfusion Proceedings of the Nineteenth International Symposium on Blood Transfusion, Groningen 1994, Organized by the Red Cross Blood Bank Groningen-drenthe.

General Material Designation

[Book]

First Statement of Responsibility

Smit Sibinga, C.th.; Das, P.C.; Brit︠, E.

Name of Publisher, Distributor, etc.

Springer Verlag

Date of Publication, Distribution, etc.

2012

Specific Material Designation and Extent of Item

pages

Text of Note

I. Blood coagulation: molecular biology of haemophilia, various types of von Willebrand disease and thrombophilia. II. Haemoglobin and red cells: globin gene regulation, molecular pathology of thalassaemia syndromes, options for bone marrow transplantation and gene therapy for haemoglobinopathies, molecular biology and genetic abnormalities in blood group serology. III. White cells and malignancies: role of the Blood Bank in human gene therapy trials and translocations in cancer, mechanism of oncogenic conversion and implications for therapy, role of topoisomerase IIalpha and beta isozymes in determining intrinsic and acquired drug resistance. IV. Gene technology, ethics and the future: ethics of genetic manipulation, impact of cell culture technology on transfusion medicine, strategies for making gene therapy work, the role of the Blood Bank in gene therapy.

Smit Sibinga, C.th.; Das, P.C.; Brit︠, E.

Smit Sibinga, C.th.; Das, P.C.; Brit︠, E.

Electronic name

[Book]

Y