عنوان

Translational medicine and drug discovery /

(Number (ISBN

0521886457 (hardback)

(Number (ISBN

9780521886451 (hardback)

Number

b527894

Title Proper

Translational medicine and drug discovery /

General Material Designation

[Book]

First Statement of Responsibility

edited by Bruce H. Littman, Rajesh Krishna

Place of Publication, Distribution, etc.

New York :

Name of Publisher, Distributor, etc.

Cambridge University Press,

Date of Publication, Distribution, etc.

2011

Specific Material Designation and Extent of Item

xx, 361 p. :

Other Physical Details

ill. ;

Dimensions

26 cm

Text of Note

Includes bibliographical references and index

Text of Note

Section I. Translational medicine: history, principles and application in drug development: 1. Translational medicine:definition, history, and strategies/ Bruce H. Littman -- 2. Translational medicine and its impact on diabetes drug development / Roberto A. Calle and Ann E. Taylor -- 3. Challenges in atherosclerosis / John S. Millar -- 4. Obesity: new mechanisms and translational paradigms / Gregory Gaich and David E. Moller -- 5. Bone disorders: translational medicine case studies / S. Aubrey Stoch -- 6. Case studies in neuroscience: unique challenges and examples / Gerard J. Marek -- 7. Translational medicine in oncology / Dominic G. Spinella; Section II. Biomarkers and public-private partnerships: 8. Biomarker validation and application in early drug development: idea to proof of concept/ Pfizer Global Research and Development, 2004 -- 9. Image biomarkers in drug development: case studies / Johannes T. Tauscher and Adam J. Schwarz -- 10. European new safe and innovative medicine initiatives: history and progress (through December 2009) / Ole J. Bjerrum and Hans H. Linden -- 11. Critical path institute and the predictive safety testing consortium / Elizabeth Gribble Walker -- 12. The biomarker consortium: facilitating the development and qualification of novel biomarkers through a precompetitive public-private partnership / David Wholley and David B. Lee; Section III. Future Directions: 13. Improving the quality and productivity of pharmacometric modeling and simulation activities: the foundation for model-based drug development / Thaddeus H. Grasela, Jill Fiedler-Kelly, and Robert Slusser -- 14. Embracing change: a pharmaceutical industry guide to the 21st century / Mervyn Turner

0

Text of Note

"Focuses on the new discipline of translational medicine as it pertains to drug development within the pharmaceutical and biotechnology industry"--Provided by publisher

Drug development

Molecular pharmacology

Drug Discovery

Translational Medical Research-- methods

Number

Edition

Class number

Book number

Class number

Class number

Book Number

Krishna, Rajesh

Littman, Bruce H.,1944-

Date of Transaction

20110707010907.0

Electronic name

[Book]

Y