Revised edition of: Kelley's textbook of rheumatology / Edward D. Harris, Jr. [and others]. c2005.
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
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Includes bibliographical references and index.
CONTENTS NOTE
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Anticytokine therapies -- Cell-targeted biologics and emerging targets: rituximab, abatacept, and other biologics -- Chronic musculoskeletal pain -- Arthritis self-management -- Psychosocial management of rheumatic diseases -- Nutrition and rheumatic diseases -- Introduction to physical medicine and rehabilitation -- V. II -- Etiology and pathogenesis of rheumatoid arthritis -- Clinical features of rheumatoid arthritis -- Treatment of rheumatoid arthritis -- Felty's syndrome -- Sjören's syndrome -- Ankylosing spondylitis -- Undifferentiated spondyloarthritis and reactive arthritis -- Psoriatic arthritis -- Enteropathic arthritis -- Pathogenesis of systemic lupus erythematosus -- Clinical features and treatment of systemic lupus erythematosus -- Antiphospholipid syndrome -- Systemic sclerosis and the scleroderma-spectrum disorders -- Inflammatory diseases of muscle and other myopathies -- Overlap syndromes -- The classification and epidemiology of systemic vasculitis -- Giant cell arteritis, polymyalgia rheumatica, and takayasu's arteritis -- Antineutrophil cytoplasmic antibody-associated vasculitis -- Polyarteritis and related disorders -- Isolated angiitis of the central nervous system -- Immune complex-mediated small vessel vasculitis -- Behçet's disease -- Gout and hyperuricemia -- Diseases associated with articular deposition of calcium pyrophosphate dihydrate and basic calcium phosphate crystals -- Pathogenesis of osteoarthritis -- Clinical features of osteoarthritis -- Management of osteoarthritis -- Metabolic bone disease -- Proliferative bone diseases -- Osteonecrosis -- Relapsing polychondritis -- Heritable diseases of connective tissue -- Juvenile idiopathic arthritis -- Systemic lupus erythematosus, juvenile dermatomyositis, scleroderma, and vasculitis -- Bacterial arthritis -- Lyme disease -- Mycobacterial infections of bones and joints -- Fungal infections of the bones and joints -- Rheumatic manifestations of human immunodeficiency virus infection -- Viral arthritis -- Poststreptoccocal arthritis and rheumatic fever -- Amyloidosis -- Sarcoidosis -- Hemochromatosis -- Hemophilic arthropathy -- Rheumatic manifestations of hemoglobinopathies -- Arthritis accompanying endocrine and metabolic disorders -- Musculoskeletal syndromes in malignancy -- Familial autoinflammatory syndromes -- Tumors and tumor-like lesions of joints and related structures.
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V. I: -- Biology of the normal joint -- Synovium -- Cartilage and chondrocytes -- Biology, physiology, and morphology of bone -- Muscle: anatomy, physiology, and biochemistry -- Joint biomechanics: the role of mechanics and joint pathology -- Proteinases and matrix degradation -- Mononuclear phagocytes in rheumatic diseases -- T lymphocytes -- B cells -- Fibroblasts and fibroblast-like synoviocytes -- Neutrophils and eosinophils -- Mast cells -- Platelets and rheumatic diseases -- Autoimmunity -- Innate immunity -- Adaptive immunity including organization of lymphoid tissues -- Genetics of rheumatic diseases -- Complement system -- Signal transduction -- Prostaglandins, leukotrienes, and related compounds -- Cell recruitment and angiogenesis -- Cell survival and death in rheumatic diseases -- Animal models of inflammatory arthritis -- Neurologic regulation of inflammation -- Atherosclerosis in rheumatoid arthritis -- Principles of epidemiology in rheumatic disease -- Economic burden of rheumatic diseases -- Clinical trial design and analysis -- Assessment of health outcomes -- Biologic markers -- Occupational and recreational musculoskeletal disorders -- Integrative medicine in rheumatology: an evidence-based approach -- History and physical examination of the musculoskeletal system -- Monarticular arthritis -- Polyarticular arthritis -- Fibromyalgia -- Neck pain -- Shoulder pain -- Low back pain -- Hip and knee pain -- Foot and ankle pain -- Hand and wrist pain -- Temporomandibular joint pain -- The eye and rheumatic diseases -- The skin and rheumatic diseases -- Synovial fluid analysis, synovial biopsy, and synovial pathology -- Arthrocentesis and injection of joints and soft tissue -- Antinuclear antibodies -- Rheumatoid factors and other autoantibodies in rheumatoid arthritis -- Acute-phase reactants and the concept of inflammation -- Imaging modalities in rheumatic disease -- Nonsteroidal anti-inflammatory drugs -- Glucocorticoid therapy -- Methotrexate, leflunomide, sulfasalazine, hydroxychloroquine, and combination therapies -- Immunoregulatory drugs.
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SUMMARY OR ABSTRACT
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Designed to help the specialist better understand today's scientific underpinnings of rheumatic diseases. This edition includes detailed coverage of the latest breakthroughs and the newest clinical algorithms, new chapters that help identify key effector mechanisms in autoimmune diseases and inflamation and apply the newest therapeutic modalities, and offers expanded coverage of imaging modalities to aid in diagnosing, monitoring, and managing rheumatic disease more effectively.