Safety and General Principles of Botulinum Toxin Therapies: Pearls From Across Medical Fields -- Biology and Mechanism of Action -- Botulinum Toxin for Neurogenic Detrusor Overactivity -- Overactive Bladder and Idiopathic Detrusor Overactivity -- BoNT for Bladder and Pelvic Pain -- Pediatric Botulinum Toxin Applications -- Botulinum Toxin Injection for Prostate Disorders -- Sphincter and Pelvic Floor Disorders Applications -- Non-urological Uses of Toxin with Genitourinary Insight -- Health Economics of Botulinum Toxin Application -- Perspectives from Around the World: Panorama of Where We Are and Where We Are Going