عنوان

Checkpoint controls and targets in cancer therapy /

(Number (ISBN

1607611783 (e-isbn)

(Number (ISBN

9781607611783 (e-isbn)

Erroneous ISBN

1607611775

Erroneous ISBN

9781607611776

Number

b509581

Title Proper

Checkpoint controls and targets in cancer therapy /

General Material Designation

[Book]

First Statement of Responsibility

edited by Zahid H. Siddik.

Place of Publication, Distribution, etc.

New York :

Name of Publisher, Distributor, etc.

Humana Press,

Date of Publication, Distribution, etc.

[2010]

Date of Publication, Distribution, etc.

©2010

Specific Material Designation and Extent of Item

1 online resource (xiv, 273 pages) :

Other Physical Details

illustrations (some color).

Series Title

Cancer drug discovery and development

Text of Note

Includes bibliographical references and index

Text of Note

1. Circuitry of Checkpoint Response -- Evasion of G1 Checkpoints in Cancer -- Distinct Pathways Involved in S-Phase Checkpoint Control -- Mechanisms of G2 Phase Arrest in DNA Damage-Induced Checkpoint Response -- 2. Checkpoint Response and the Aetiology of Cancer -- Chromatin Modifications and Orchestration of Checkpoint Response in Cancer -- DNA Damage Response and the Balance Between Cell Survival and Cell Death -- Dysfunction of the RB Retinoblastoma Gene in Cancer -- G1 Phase Cyclins in Cancer Development and Progression -- The BRCA1/2 Pathway Prevents Some Leukemias and Lymphomas in Addition to Breast/Ovarian Cancers: Malignancies that Overcome Checkpoint Controls -- 3. Targeting Checkpoint Response in Cancer Therapy -- Regulation of p53 Activity and Associated Checkpoint Controls -- The Importance of p53 Signaling in the Response of Cells to Checkpoint Inhibitors -- Targeting p21-Dependent Pathways for Cell Death in Cancer Therapy -- p27Kip1 as a Biomarker and Target for Treatment of Cancer -- Targeting Cyclin-Dependent Kinases with Small Molecule Inhibitors -- Chk1 and Chk2 as Checkpoint Targets -- Targeting Cdc25 Phosphatases in Cancer Therapy

0

Title

Checkpoint controls and targets in cancer therapy.

International Standard Book Number

9781607611776

Title

OhioLINK electronic book center (Online)

Title

SpringerLink

Antineoplastic agents-- Development.

Cancer cells-- Growth-- Regulation.

Cellular control mechanisms.

Antineoplastic Agents-- pharmacology.

Cell Cycle-- drug effects.

Cell Cycle Proteins-- drug effects.

Drug Resistance, Neoplasm.

Neoplasms-- drug therapy.

Number

Edition

Class number

Book number

Siddik, Zahid H.

Ohio Library and Information Network.

Date of Transaction

20111212092307.0

Cataloguing Rules (Descriptive Conventions))

rda

Electronic name

[Book]

Y