عنوان

Chemical library design

(Number (ISBN

160761930X

(Number (ISBN

1607619318

(Number (ISBN

9781607619307

(Number (ISBN

9781607619314

Number

b505173

Title Proper

Chemical library design

General Material Designation

[Book]

First Statement of Responsibility

edited by Joe Zhongxiang Zhou.

Place of Publication, Distribution, etc.

New York, NY :

Name of Publisher, Distributor, etc.

Humana Press,

Date of Publication, Distribution, etc.

c2011.

Series Title

Methods in molecular biology,

Series Title

Springer protocols

Volume Designation

685

ISSN of Series

1064-3745 ;

Text of Note

Includes bibliographical references and index.

Text of Note

Historical overview of chemical library design / Roland E. Dolle -- Chemoinformatics and library design / Joe Zongxiang Zhou -- Molecular library design using multi-objective optimization methods / Christos A. Nicolaou and Christos C. Kannas -- A scalable approach to combinatorial library design / Puneet Sharma, Srinivasa Salapaka, and Carolyn Beck -- Application of Free-Wilson selectivity analysis for combinatorial library design / Simone Sciabola ... [et al.] -- Application of QSAR and shape pharmacophore modeling approaches for targeted chemical library design / Jerry O. Ebalunode, Weifan Zheng, and Alexander Tropsha -- Combinatorial library design from reagent pharmacophore fingerprints / Hongming Chen, Ola Engkvist, and Niklas Blomberg -- Docking methods for structure-based library design / Claudio N. Cavasotto and Sharangdhar S. Phatak -- Structure-based library design in efficient discovery of novel inhibitors / Shunqi Yan and Robert Selliah -- Structure-based and property-compliant library design of 11[beta]-HSD1 adamantyl amide inhibitors / Genevieve D. Paderes ... [et al.] -- Design of screening collections for successful fragment-based lead discovery / James Na and Qiyue Hu -- Fragment-based drug design / Eric Feyfant ... [et al.] -- LEAP into the Pfizer Global Virtual Library (PGVL) space : creation of readily synthesizable design ideas automatically / Qiyue Hu ... [et al.] -- The design, annotation, and application of a kinase-targeted library / Hualin Xi and Elizabeth A. Lunney -- PGVL hub : an integrated desktop tool for medicinal chemists to streamline design and synthesis of chemical libraries and singleton compounds / Zhengwei Peng ... [et al.] -- Design of targeted libraries against the human Chk1 kinase using PGVL hub / Xengwei Peng and Qiyue Hu -- GLARE : a tool for product-oriented design of combinatorial libraries / Jean-François Truchon -- CLEVER : a general design tool for combinatorial libraries / Tze Hau Lam ... [et al.].

0

Cheminformatics.

Combinatorial chemistry.

Drugs-- Design.

Combinatorial Chemistry Techniques-- methods.

Drug Discovery-- methods.

Medical Informatics-- methods.

Pharmaceutical Preparations-- chemistry.

Small Molecule Libraries.

Zhou, Joe Zhongxiang.

Date of Transaction

20181223152734.0

Electronic name

[Book]

Y