edited by Lucy G. Andrews and Trygve O. Tollefsbol
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
Paisley :
Name of Publisher, Distributor, etc.
Quantum [distributor],
Date of Publication, Distribution, etc.
2007
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
x, 193 p. :
Other Physical Details
ill. ;
Dimensions
24 cm
SERIES
Series Title
Methods in molecular biology ;
Volume Designation
405
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index
CONTENTS NOTE
Text of Note
Methods of telomerase inhibition -- Telomerase inhibition by synthetic nucleic acids and chemosensitization in human bladder cancer cell lines -- hTERT knockdown in human embryonic kidney cells using double-stranded RNA -- RNA interference using a plasmid construct expressing a short-hairpin RNA -- Retrovirus-mediated RNA interference -- Telomerase inhibition and telomere targeting in hematopoietic cancer cell lines with small non-nucleosidic synthetic compounds (BIBR1532) -- Uses of telomerase peptides in anti-tumor immune therapy -- Establishing cell-based reporter systems for the analysis of hTERT expression -- Telomerase RNA inhibition using antisense oligonucleotide against human telomerase RNA linked to a 2',5'-oligoadenylate -- Knockdown of telomerase RNA using hammerhead ribozymes and RNA interference -- Evaluation of tankyrase inhibition in whole cells -- Inhibition of telomerase by targeting MAP kinase signaling -- Screening of telomerase inhibitors -- Telomerase inhibition combined with other chemotherapeutic reagents to enhance anti-cancer effect