Reviews the state of the art in the management of squamous cell head and neck cancer, with emphasis on coordinating different treatment modalities. The authors address several surgical issues, including laser-based surgery, larynx preservation approaches, salvage surgery, and neck management after non-operative treatment. They also discuss definite radiation for larynx cancer, brachytherapy, altered fractionation radiation, intensity modulated radiation therapy, and the imporatance of tumor hypoxia, as well as the role of chemotherapy in sequential, concurrent, and adjuvant multimodality treatment schedules.