Techniques and methodological approaches in breast cancer research /
General Material Designation
[Book]
First Statement of Responsibility
Jose Russo, Irma H. Russo
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
1 online resource
GENERAL NOTES
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Includes index
CONTENTS NOTE
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Laser Capture Microdissection as a Tool for Compartmentalization Studies -- Histological Evaluation of the Normal Breast -- Methodology for Studying the Compartments of the Human Breast -- Methodological approach to Tissue Micro Array for Studying the Normal and Cancerous Human Breast -- In Vitro Techniques for Studying the Normal Breast and the use of Cell Lines in Breast Cancer Research -- In situ Methods for Indentifying the Stem Cell of the Normal and Cancerous Breast -- Imaging Techniques for Evaluation in vitro Behavior of Normal and Cancerous Breast Tissue -- In vivo Studies of Breast Cancer Cells -- RNA Sequencing in the Human Breast -- Methodological Approaches for the Understanding the Epigenetic Landscape of the of the Human Breast and its Implications in Cancer and Prevention
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SUMMARY OR ABSTRACT
Text of Note
This volume explores the myriad of techniques and methodological approaches that are being used in?breast cancer research. The authors critically evaluate of the advantages and disadvantages of current methodologies,?starting with the tools available for understanding?the architecture of the human breast, including?its tissue and cellular composition.?The volume discusses?the importance of?functional studies in breast cancer research, especially with the help of?laser capture microdissection, which allows the separation of small amounts of tissue, as well as specific cells, for biochemical ana