عنوان

Tumor-induced immune suppression :

(Number (ISBN

1489980563

(Number (ISBN

9781489980564

Erroneous ISBN

1489980555 (print)

Erroneous ISBN

9781489980557

Erroneous ISBN

9781489980557 (print)

Number

dltt

Title Proper

Tumor-induced immune suppression :

General Material Designation

[Book]

Other Title Information

mechanisms and therapeutic reversal /

First Statement of Responsibility

Dmitry I. Gabrilovich, Arthur A. Hurwitz, editors

Edition Statement

Second edition

Edition Statement

Second edition

Specific Material Designation and Extent of Item

1 online resource (ix, 301 pages) :

Other Physical Details

illustrations

Text of Note

Includes bibliographical references and index

Text of Note

Regulatory T Cells and Cancer -- Th17 cells in cancer -- Mast cells and immune response in cancer -- Myeloid-Derived Suppressor Cells in Tumor-Induced T-Cell Suppression and Tolerance -- Immunobiology of Dendritic Cells in Cancer -- Macrophages and Tumor Development -- Angiogenesis and Immune Suppression in Cancer -- Tim-3 Regulation of Cancer Immunity.-Transcriptional Regulation of Dendritic Cells in The Tumor Microenvironment -- S100A9, Inflammation, and Regulation of Immune Suppression in Cancer -- IDO in Inflammatory Programming and Immune Suppression in Cancer -- Defining the Fate and Function of Effector T cells through Galectin-1 Galectin-1 Ligand Binding Interactions: Implications in Tumor Immunity -- Arginine Metabolism, a Major Pathway for the Suppressive Function of Myeloid-derived Suppressor Cells.-The Hypoxia-Adenosinergic Immunosuppression and Redirection of Immune Response in Tumor Microenvironment -- Molecular Pathways in Antigen Presenting Cells Involved in the Induction of Antigen-Specific T-Cell Tolerance -- Overcoming Immune Suppression: Therapeutic Strategies Targeting T-Cell Function in Cancer

0

Text of Note

Tumor-Induced Immune Suppression - Prospects and Progress in Mechanisms and Therapeutic Reversal presents a comprehensive overview of large number of different mechanisms of immune dysfunction in cancer and therapeutic approaches to their correction. This includes the number of novel mechanisms that has never before been discussed in previous monographs. The last decades were characterized by substantial progress in the understanding of the role of the immune system in tumor progression. Researchers have learned how to manipulate the immune system to generate tumor specific immune response, which raises high expectations for immunotherapy to provide breakthroughs in cancer treatment. It is increasingly clear that tumor-induced abnormalities in the immune system not only hampers natural tumor immune surveillance, but also limits the effect of cancer immunotherapy. Therefore, it is critically important to understand the mechanisms of tumor-induced immune suppression to make any progress in the field and this monograph provides these important insights

International Standard Book Number

9781489980557

Immunosuppression.

Tumors-- Immunological aspects.

Immunotherapy-- methods.

Neoplasms-- immunology.

Neoplasms-- therapy.

T-Lymphocytes-- immunology.

T-Lymphocytes, Regulatory.

HEA-- 039000

MED-- 014000

MED-- 022000

MED-- 045000

MED-- 112000

Number

Edition

Class number

Gabrilovich, Dmitry I.

Hurwitz, Arthur A.

Ohio Library and Information Network.

Date of Transaction

20201222074507.0

Cataloguing Rules (Descriptive Conventions))

pn

Electronic name

[Book]

270410

Y