Separation mechanisms in hydrophilic interaction chromatography -- Stationary phases for HILIC -- HILIC method development -- Pharmaceutical applications of hydrophilic interaction chromatography -- Hydrophilic interaction chromatography (HILIC) for drug discovery -- Advances in hydrophilic interaction chromatography (HILIC) for biochemical applications -- HILIC-MS for targeted metabolomics and small molecule bioanalysis -- HILIC for food, environmental, and other applications -- Theory and practice of two-dimensional liquid chromatography separations involving the HILIC mode of separation
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SUMMARY OR ABSTRACT
Text of Note
"Covers in detail HILIC retention mechanism, including background on the HILIC mode, what differences it from other HPLC modes, and retention mechanisms that can come into play"--
Text of Note
"This book provides background information, guidance for method development, and a discussion of applications in the field of hydrophilic interaction chromatography (HILIC.) The book serves as a valuable reference tool for scientists confronted with an analysis problem involving polar compounds to determine if HILIC would be a good choice to pursue and helps them in choosing initial experimental conditions. The book gives a detailed description of the HILIC retention mechanisms and specific information regarding application areas spanning a wide range of industries.Topics include: HILIC retention mechanisms, Stationary Phases for HILIC, HILIC Method Development, Pharmaceutical and Other Applications of HILIC, HILIC for Drug Discovery, HILIC in Two-Dimensional Separations"--