Chapter 1: Introduction -- Chapter 2: Principles of drug movement in the body -- Chapter 3: Quantitative structure-permeability relationships / with Xin-Rui Xia -- Chapter 4: Absorption -- Chapter 5: Distribution / with Jennifer Buur -- Chapter 6: Renal elimination -- Chapter 7: Hepatic biotransformation and biliary excretion / with Ronald Baynes -- Chapter 8: Compartmental models -- Chapter 9: Noncompartmental models -- Chapter 10: Nonlinear models -- Chapter 11: Physiological models / with Teresa Leavens -- Chapter 12: Dosage regimens -- Chapter 13: Simultaneous pharmacokinetic-pharmacodynamic modeling / with Pierre-Louis Toutain -- Chapter 14: Study design and data analysis / with Jason Chittenden - Chapter 15: Bioequivalence Studies / with Marilyn Martinez -- Chapter 16: Population pharmacokinetic models / with Jason Chittenden -- Chapter 17: Dosage adjustments in disease states / with Jennifer Davis -- Chapter 18: Interspecies extrapolations -- Chapter 19: Tissue residues and withdrawal times / with Sharon Mason
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Text of Note
"Now in a newly revised edition, Comparative Pharmacokinetics presents the principles and techniques of pharmacokinetics in a detailed, yet practical and easily understandable manner. Coverage includes an overview of the basic physiologic processes of drug absorption and disposition and detailed explanation of pharmacokinetic means of measuring and predicting these processes by way of mechanistic and empirical models, as well as extensive coverage of dosage regimens and adjustments, interspecies extrapolation, experimental design, data collection and analysis, and residues and withdrawal times"--Provided by publisher