The Role of Protective Groups in Organic Synthesis -- Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols -- Protection for Phenols and Catechols -- Protection for the Carbonyl Group -- Protection for the Carboxyl Group -- Protection for the Thiol Group -- Protection for the Amino Group -- Protection for the Alkyne-CH -- Protection for the Phosphate Group -- Reactivities, Reagents, and Reactivity Charts
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SUMMARY OR ABSTRACT
Text of Note
This edition provides readers with a comprehensive compendium of 1,050 of the most useful protective groups as well as 5,350 references to original publications. Protective groups are organized by six major organic functional groups: hydroxyl, amino, carboxyl, carbonyl, sulfhydryl, and phosphate groups (the last new to this edition). Also added in this edition are protection of the alkyne-CH, expanded coverage of protection of all groups, and many new enzymatic methods of protection and deprotection. Each chapter briefly describes the classes of available protective groups, followed by an in-depth look at the chemistry of individual protective groups, their properties, and the best methods of formation and cleavage. Ten reactivity charts with more than 28,000 entries summarize the relative reactivities of 270 commonly used protective groups with 108 reagents
OTHER EDITION IN ANOTHER MEDIUM
Title
Protective groups in organic synthesis.
TOPICAL NAME USED AS SUBJECT
Organic compounds-- Synthesis
Protective groups (Chemistry)
LIBRARY OF CONGRESS CLASSIFICATION
Class number
QD262
Book number
.
G665
1999
PERSONAL NAME - PRIMARY RESPONSIBILITY
Greene, Theodora W., (Theodora Whatmough),1931-2005