Introduction to the glucose sensing problem -- The macrophage in wound healing surrounding implanted devices -- Strategies to overcome biological barriers to biosensing -- A window to observe the foreign body reaction to glucose sensors -- Commercially available continuous glucose monitoring systems -- Membrane-based separations applied to in vivo glucose sensing : microdialysis and ultrafiltration sampling -- Transdermal microfluidic continuous monitoring systems -- Redundant arrays and next generation sensors -- Nitric-oxide releasing subcutaneous glucose sensors -- Fluorescence-based glucose sensors -- The use of single walled carbon nanotubes for optical glucose detection -- Introduction to spectroscopy for noninvasive glucose sensing -- Near infrared spectroscopy for noninvasive glucose sensing -- Non-invasive glucose sensing with Raman spectroscopy -- Surface enhanced Raman spectroscopy for glucose sensing