عنوان
پدید آورنده
موضوع
رده
کتابخانه
محل استقرار
INTERNATIONAL STANDARD BOOK NUMBER
(Number (ISBN
012415784X (hbk.)
(Number (ISBN
9780124157842 (hbk.)
NATIONAL BIBLIOGRAPHY NUMBER
Number
dltt
TITLE AND STATEMENT OF RESPONSIBILITY
Title Proper
Translational endocrinology of bone :
General Material Designation
[Book]
Other Title Information
reproduction, metabolism, and the central nervous system /
First Statement of Responsibility
edited by Gerard Karsenty
EDITION STATEMENT
Edition Statement
1st ed
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
Waltham, MA :
Name of Publisher, Distributor, etc.
Academic,
Date of Publication, Distribution, etc.
2012
PROJECTED PUBLICATION DATE
Date
201210
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
x, 226 p. :
Other Physical Details
ill. (some col.) ;
Dimensions
28 cm
GENERAL NOTES
Text of Note
"Elsevier science & technology books."
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index
SUMMARY OR ABSTRACT
Text of Note
Karsenty (genetics and development, Columbia U.) compiles 17 articles by researchers from Europe, the US, Australia, and Japan who discuss the effects of bone on whole-organism physiology and how the study of this discipline aids in the understanding of the pathogenesis of degenerative diseases affecting several organs. Chapters address various hormones and neuromediators ranging from serotonin to osteocalcin, as well as knowledge about the ability of bone to regulate phosphate metabolism. They demonstrate, through examples of hormones emerging during evolution with bone and coordinating the regulation of bone mass accrual, energy metabolism, and reproduction, that the appearance of bone during evolution has impacted the physiology of the entire organism, and also show, through the example of the skeleton, how a genetic-based approach to the study of the physiology of a given organ can reveal multiple new functions, connections with other organs, and novel identities for well-known molecules. They discuss the basic principles of bone cell biology, the central control of bone mass, neuropeptide Y and bone formation, the gastrointestinal tract and the control of bone mass, the skeletal actions of insulin, transcriptional regulation of the endocrine function of bone, regulation of bone resorption, the clinical aspects of fibroblast growth factor 23, bone marrow fat and bone mass, and the significance of organ crosstalk in insulin resistance and type 2 diabetes. Academic Press is an imprint of Elsevier. Annotation ©2012 Book News, Inc., Portland, OR (booknews.com)
TOPICAL NAME USED AS SUBJECT
Bones-- Growth
Bones-- Metabolism-- Endocrine aspects
Bone and Bones
DEWEY DECIMAL CLASSIFICATION
Number
612
.
75
Edition
23
PERSONAL NAME - ALTERNATIVE RESPONSIBILITY
Karsenty, Gerard
ORIGINATING SOURCE
Date of Transaction
20130107084209.0
ELECTRONIC LOCATION AND ACCESS
Electronic name
مطالعه متن کتاب [Book]
Y
