Introduction: Studies with Listeria monocytogenes lead the way / Emil R. Unanue and Javier A. Carrero -- Interactions of Listeria monocytogenes with the Autophagy system of host cells / Grace Y. Lam, Mark A. Czuczman, Darren E. Higgins and John H. Brumell -- Virulence Factors that Modulate the Cell Biology of Listeria Infection and the Host Response / Serge Mostowy and Pascale Cossart -- Dendritic cells in Listeria monocytogenes infection / Brian T. Edelson -- Probing CD8 T cell responses with Listeria monocytogenes infection / Stephanie A. Condotta, Martin J. Richer, Vladimir P. Badovinac -- Listeria monocytogenes and its products as agents for Cancer Immunotherapy / Patrick Guirnalda, Laurence Wood, Yvonne Paterson -- Monocyte-mediated immune defense against murine Listeria monocytogenes infection / Natalya V. Serbina, Chao Shi and Eric G. Pamer -- Innate immune pathways triggered by Listeria monocytogenes and their role in the induction of cell-mediated immunity / Chelsea E. Witte, Kristina A. Archer, Chris S. Rae, John-Demian Sauer, Josh J. Woodward, and Daniel A. Portnoy -- Mechanisms and immunological effects of lymphocyte apoptosis caused by Listeria monocytogenes / Javier A. Carrero and Emil R. Unanue