عنوان

Fragment-based drug discovery /

(Number (ISBN

1849739080

(Number (ISBN

9781849739085

Erroneous ISBN

9781782620938 (PDF eISBN)

Number

dltt

Title Proper

Fragment-based drug discovery /

General Material Designation

[Book]

First Statement of Responsibility

edited by Steven Howard, Chris Abell

Specific Material Designation and Extent of Item

xlix, 264 pages :

Other Physical Details

illustrations (colour) ;

Dimensions

25 cm

Series Title

RSC drug discovery,

Volume Designation

47

ISSN of Series

2041-3203 ;

Text of Note

Includes bibliographical references and index

Text of Note

Machine generated contents note: ch. 1 Different Flavours of Fragments / Claudio Dagostin -- 1.1.Fragment-Based Drug Discovery -- 1.2.Different Types of Fragments -- 1.3.How We Identify Fragments -- 1.4.Selectivity -- 1.5.Applications of Fragment-Based Methods -- 1.5.1.Assigning Function -- 1.5.2.Assessing Ligandability -- 1.5.3.Speeding Up Chemical Validation -- 1.6.Targeting Protein -- Protein Interactions and Beyond -- 1.7.Targeting Oligonucleotides -- 1.8.Concluding Remarks -- References -- ch. 2 Getting the Most Value from Your Screens: Advances in Hardware, Software, and Methodologies to Enhance Surface Plasmon Resonance Based Fragment Screening and Hit-to-Lead Support / Brandon J. Bravo -- 2.1.Introduction -- 2.2.SPR Technology as Applied to FBS -- 2.3.The Basic Screening Cascade -- 2.4.Advances in Data Reduction and Active Selection in Primary Screening -- 2.4.1.Robust Drift Correction by Local Estimation -- 2.4.2.Method #1 for Hit Detection: Box Plots --

0

Drug development

Ligands (Biochemistry)

Drug Discovery

Ligands

Number

Edition

Class number

Book number

Class number

Class number

Abell, C.

Howard, Steven,PhD

Royal Society of Chemistry (Great Britain),publisher

Date of Transaction

20160322033443.0

Cataloguing Rules (Descriptive Conventions))

rda

Electronic name

[Book]

Y