Advanced textbook on gene transfer, gene therapy, and genetic pharmacology :
General Material Designation
[Book]
Other Title Information
principles, delivery, and pharmacological and biomedical applications of nucleotide-based therapies /
First Statement of Responsibility
editor, Daniel Scherman
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
xi, 544 pages :
Other Physical Details
illustrations (some color) ;
Dimensions
27 cm
SERIES
Series Title
ICP textbooks in biomolecular sciences ;
Volume Designation
v. 1
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index
CONTENTS NOTE
Text of Note
Basic definitions and general principles -- History of gene therapy -- Genetic pharmacology using synthetic deoxyribonucleotides -- Principles of RNAi trigger expression for gene therapy -- On-demand alternative splicing for gene rescue -- Nuclease-mediated targeted genetic correction -- Retrovirus and lentivirus-derived vectors -- Adenovirus vectors -- Adeno-associated virus (AAV) vectors -- Herpes simplex virus HSV-1-based vectors -- Non-viral DNA vectors -- Macromolecular conjugates for non-viral nucleic acid delivery -- Auto-associative systems for non-viral nucleic acid delivery : lipids -- Hydrodynamic-pressure-based non-viral nucleic acid delivery -- Electrotransfer/electroporation for non-viral nucleic acid delivery -- Imaging of gene delivery -- Oncolytic adenoviruses for cancer gene therapy -- Progress in DNA vaccine approaches for cancer immune therapy -- Gene therapy of the beta-hemoglobinopathies -- Gene therapy for hemophilia A and B -- Experimental and clinical ocular gene therapy -- Gene therapy of neurological diseases -- Genetic therapy of muscle diseases : Duchenne muscular dystrophy -- Induced pluripotent stem cells for regenerative medicine -- Production and purification of viral vectors -- Production and purification of plasmid vectors