عنوان
پدید آورنده
موضوع
رده
R857.T55
R857
.
T55
کتابخانه
محل استقرار
INTERNATIONAL STANDARD BOOK NUMBER
(Number (ISBN
1493932284
(Number (ISBN
9781493932283
Erroneous ISBN
1493932276
Erroneous ISBN
9781493932276
NATIONAL BIBLIOGRAPHY NUMBER
Number
dltt
TITLE AND STATEMENT OF RESPONSIBILITY
Title Proper
Regenerative medicine for degenerative muscle diseases /
General Material Designation
[Book]
First Statement of Responsibility
Martin K. Childers, editor
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
1 online resource (xiii, 336 pages) :
Other Physical Details
illustrations (some color).
SERIES
Series Title
Stem cell biology and regenerative medicine,
ISSN of Series
2196-8985
GENERAL NOTES
Text of Note
Includes index
CONTENTS NOTE
Text of Note
Preface; About the Editor; Contents; Chapter 1: Regenerative Medicine Approaches to Degenerative Muscle Diseases; 1.1 Background; 1.1.1 What Is Regenerative Medicine?; 1.1.2 Degenerative Muscle Diseases Are Rare, but Rare Diseases Are Common; 1.2 What Disorders Lead to Chronic Muscle Degeneration?; 1.2.1 Myopathies; 1.2.2 Acquired Myopathies; 1.2.3 Congenital Myopathies; 1.2.4 Muscular Dystrophies; 1.3 Can Human Cells Be Transplanted to Regenerate Damaged Muscles?; 1.3.1 Adult Stem Cells; 1.3.2 Embryonic Stem Cells; 1.3.3 Cellular Reprogramming
Text of Note
1.4 What Is Gene Therapy and When Will It Be Used in Clinical Practice?1.5 Will Gene Replacement Therapy Be Useful for Inherited Muscle Diseases like Muscular Dystrophy?; 1.6 Can Genes Be Repaired?; 1.7 Can Gene Replacement Therapy Rescue Lethal Muscle Disease? Lessons Learned from Dogs; References; Chapter 2: An Overview of rAAV Vector Product Development for Gene Therapy; 2.1 Vector Design and Lead Identification; 2.2 Product Manufacturing; 2.2.1 Scale; 2.2.2 Reagents and Materials; 2.2.3 Process Design and Development; 2.2.4 Upstream Processing; 2.2.5 Downstream Processing
Text of Note
2.2.6 Formulation, Fill, Finish, and Product Configuration2.3 Analytical Testing; 2.3.1 Assay Design and Development; 2.3.2 Assay Qualification; 2.3.3 Sampling and Testing; 2.3.4 Product Specifications Setting; 2.3.5 Stability Testing; 2.4 Toxicology Studies; 2.5 Clinical Trials; 2.6 Regulatory; 2.6.1 Expedited Programs; 2.7 Commercial; References; Chapter 3: Gene Discovery in Congenital Myopathy; 3.1 Congenital Myopathies; 3.1.1 Overview; 3.1.2 Nemaline Myopathies; 3.1.2.1 Clinical Features; 3.1.2.2 Pathological Features; 3.1.2.3 Genetics; 3.1.3 Core Myopathies; 3.1.3.1 Clinical Features
Text of Note
3.1.3.2 Pathological Features3.1.3.3 Genetics; 3.1.4 Centronuclear Myopathies; 3.1.4.1 Clinical Features; 3.1.4.2 Pathological Features; 3.1.4.3 Genetics; 3.1.5 Congenital Fiber-Type Disproportion; 3.1.5.1 Clinical and Pathological Features; 3.1.5.2 Genetics; 3.1.6 Undefined Congenital Myopathies; 3.2 Gene Discovery in Congenital Myopathies; 3.2.1 Diagnostic Challenges; 3.2.1.1 Genetic Heterogeneity; 3.2.1.2 Clinical Heterogeneity; 3.2.1.3 Lack of Specific Biomarkers; 3.2.2 Genetic Approaches; 3.2.2.1 Linkage Mapping and Positional Cloning; 3.2.2.2 Homozygosity Mapping
Text of Note
3.2.2.3 Candidate Gene Studies3.2.2.4 Next-Generation Sequencing; 3.2.3 Clinical Implications of NGS; 3.2.3.1 NGS Gene Panels; 3.2.3.2 Structural Variation; 3.3 Development of Targeted Therapies; 3.4 Conclusion; References; Chapter 4: Stem Cell Transplantation for Degenerative Muscle Diseases; 4.1 Introduction to Duchenne Muscular Dystrophy; 4.2 Stem Cell Transplantation for the Treatment of DMD; 4.2.1 Satellite Cells/Myoblasts; 4.2.2 Muscle-Derived Stem Cells; 4.2.3 Myoendothelial Cells and Pericytes; 4.2.4 Mesoangioblasts; 4.2.5 CD133+ Cells; 4.2.6 Mesenchymal Stem Cells
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OTHER EDITION IN ANOTHER MEDIUM
International Standard Book Number
9781493932276
TOPICAL NAME USED AS SUBJECT
Muscles-- Diseases.
Regenerative medicine.
DEWEY DECIMAL CLASSIFICATION
Number
616
.
02/7
Edition
23
LIBRARY OF CONGRESS CLASSIFICATION
Class number
R857
.
T55
PERSONAL NAME - ALTERNATIVE RESPONSIBILITY
Childers, Martin K.
CORPORATE BODY NAME - ALTERNATIVE RESPONSIBILITY
Ohio Library and Information Network.
ORIGINATING SOURCE
Date of Transaction
20160422040456.4
Cataloguing Rules (Descriptive Conventions))
pn
ELECTRONIC LOCATION AND ACCESS
Electronic name
مطالعه متن کتاب [Book]
Y
