A productive experiment -- Human practices: diagnosis. The setting. SynBERC: the Synthetic Biology Engineering Research Center ; Principles of design, 2006-2007: from bioethics to human practices ; Interfacing the human and biosciences 2007: three modes ; Synthetic biology 2008: from manifestos to ramifying research programs ; Lessons learned 2009: from discordancy to indeterminacy -- Human practices: inquiry. Recapitulation and reorientation 2009: the first wave of human practices ; The second wave of synthetic biology 2009: from parts to ontological domains ; A mode 3 experiment: figuring dual-use -- from safety to malice ; Toward the second wave of human practices 2010: figures of dual-use, biopower, and reconstruction ; Lessons learned 2010: from indeterminacy to discordancy