necroptotic, autophagic and other non-apoptotic mechanisms /
First Statement of Responsibility
edited by Avi Ashkenazi, James A. Wells, Junying Yuan
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
xiii, 337 pages, 26 unnumbered pages of plates :
Other Physical Details
illustrations (some color) ;
Dimensions
24 cm
SERIES
Series Title
Methods in enzymology,
Volume Designation
v.545
ISSN of Series
0076-6879 ;
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and indexes
CONTENTS NOTE
Text of Note
Assays for necroptosis and activity of RIP kinases -- IAP family of cell death and signaling regulators -- Activation of the NLRP3 inflammasome by proteins that signal for necroptosis -- Characterization of the ripoptosome and its components: implications for anti-imflammatory and cancer therapy -- Tools and techniques to study ligand-receptor interactions and receptor activation by TNF superfamily members -- Necrotic cell death in caenorhabditis elegans -- Noncanonical cell death in the nematode caenorhabditis elegans -- Autophagy and cell death in the fly -- Structural studies of death receptors -- Use of E2 ubiquitin conjugates for the characterization of ubiquitin transfer by RING E3 ligases such as the inhibitor of apoptosis proteins -- Multidimensional profiling in the investigation of small-molecule-induced cell death
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SUMMARY OR ABSTRACT
Text of Note
Regulated Cell Death Part A & Part B of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in apoptosis focusing on the important areas of intrinsic pathway, extrinsic pathway, caspases, cellular assays and post-apoptotic effects and model organisms; as well as topics on necroptosis and screening approaches. Continues the legacy of this premier serial with quality chapters authored by leaders in the field