Part I. Critical Events in Normal Development and Aging: Lung progenitor cell specification and morphogenesis -- Development of airway epithelium -- Development of the innervation of the lower airways: structure and function -- The formation of pulmonary alveoli -- Pulmonary vascular development -- Developmental physiology of the pulmonary circulation -- Development of salt and water transport across airway and alveolar epithelia -- Physical, endocrine, and growth factors in lung development -- The development of the pulmonary surfactant system -- Ontogeny of the pulmonary immune system -- Development of antioxidant and xenobiotic metabolizing enzyme systems -- Stretch and grow: mechanical forces in compensatory lung growth -- Pulmonary transition at birth -- Normal aging of the lung -- Cell-based strategies for the treatment of injury to the developed lung -- Epigenetics and the developmental origins of lung disease -- Part II. Environmental Influences on Lung Developmental and Aging: Pulmonary consequences of preterm birth -- The effects of neonatal hyperoxia on lung development -- The influence of nutrition on lung development before and after birth -- Genetic factors involved in susceptibility to lung disease -- Effects of environmental tobacco smoke during early life stages -- Nicotine exposure during early development: effects on the lung -- Exposure to allergens during development -- The epidemiology of air pollution and childhood lung diseases -- Environmental toxicants and lung development in experimental models -- Effect of environment and aging on the pulmonary surfactant system -- Environmental determinants of lung aging