edited by Howard D. Lipshitz, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada
EDITION STATEMENT
Edition Statement
First edition
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
xiii, 415 pages, 18 unnumbered pages of color lates :
Other Physical Details
illustrations ;
Dimensions
24 cm
SERIES
Series Title
Current topics in developmental biology,
Volume Designation
volume 113
ISSN of Series
0070-2153 ;
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index
CONTENTS NOTE
Text of Note
The maternal-to-zygotic transition in C. elegans / Scott Robertson and Rueyling Lin. Introduction ; Components of the MZT ; Major regulators/events that coordinate the MZT ; Concluding remarks -- Regulation and function of maternal gene products during the maternal-to-zygotic transition in Drosophila / John D. Laver [and others] ; Introduction ; Overview of oogenesis and early embryogenesis ; Maternal factors during oocyte maturation ; Maternal factors during egg activation and early embryogenesis ; The maternal-to-zygotic transition in primordial germ cells ; Conclusion and future prospects -- Transcriptional activation of the zygotic genome in Drosophila / Melissa M. Harrison and Michael B. Eisen. Introduction ; Activating transcription of the zygotic genome ; Mechanisms regulating transcriptional activation during the MZT ; Chromatin dynamics during the MZT ; The role of cis-Regulatory elements in regulating zygotic transcription ; Concluding remarks -- Coordinating cell cycle remodeling with transcriptional activation at the Drosophila MBT / Shelby A. Blythe and Eric F. Wieschaus. Introduction ; What happens at the MBT? ; Mechanisms for timing zygotic genome activation ; Concluding remarks -- Germ line versus soma in the transition from egg to embryo / S. Zachary Swartz and Gary M. Wessel. The big picture ; Are METs universal? ; General activation of the embryonic genome ; Activation of regionally specific gene regulatory networks ; Loss of cleavage synchrony : a cause of effect of embryonic control? ; Degradation of the maternally supplied transcription ; Separating the soma from the germ line : a critical fork in the road ; Different roads lead to a conserved germ line program ; PGC specification by induction ; PGC specification by preloading ; Evolutionary transition of PGC segregation in the echinoderms ; Putting your germ cells in the freezer : possible advantages for preloaded specification ; Are METs different between the germ line and soma? : transcriptional repression in PGCs ; Differential stability of mRNA in the germ line and soma ; NMETs are delayed in PGCs ; A continuum of maternal and embryonic contributions to development -- The maternal-to-zygotic transition during vertebrate development : a model for reprogramming / Valeria Yartseva and Antonio J. Giraldez. Introduction ; Mechanisms to maternal mRNA clearance during the MZT ; Consequences of failure of maternal mRNA clearance ; MZT connection to other transitions and reprogramming ; Concluding remarks -- Building the future : post-transcriptional regulation of cell fate decisions prior to the Xenopus midblastula transition / Michael D. Sheets. Introduction ; Regulation of maternal mRNAs in the Xenopus embryo ; miRNA regulation of mRNAs during early Xenopus development ; Translational control of mRNAs encoding cell fate determinants - Regulation of maternal proteins in the Xenopus embryo ; Regulated proteolysis and the control of maternal signaling pathways ; The Xenopus maternal proteome ; The maternal phosphoproteome ; Metabolism and metabolomics ; Conclusions -- The Xenopus maternal-to-zygotic transition from the perspective of the germline / Jing Yang [and others]. Introduction ; Germ-plasm RNAs and cytoskeletal dynamics : stage VI Oocyte ; Germ plasm and cytoskeletal dynamics : oocyte maturation/fertilization ; Maternal determinants for two lineages inherited by the same blastomeres : a dilemma ; Mechanisms for protecting the germline during the MZT ; PGCs are transcriptionally repressed at the MBT ; How does the germline escape the MBT? ; RNA degradation during the MZT ; Stability of germline RNAs and proteins ; The PGC late-gastrula transition -- Sculpting the transcriptome during the oocyte-to-embryo transition in mouse / Petr Svoboda [and others]. Introduction ; Overview of significant events during OET ; The OET : the mother of all transcriptome remodeling -- The maternal-to-zygotic transition in flowering plants : evidence, mechanisms, and plasticity / Celia Baroux and Ueli Grossniklaus. Seed development ; a largely maternal affair ; Emancipation of the plant embryo ; Progressive zygotic gene activation ; Mechanisms of zygotic genome activation ; The dynamics of the maternal-to-zygotic transition vary depending on plant species and genetic background ; Biological functions of the maternal-to-zygotic transition in plants ; Unresolved questions and outlook -- the maternal-to-zygotic transition in higher plants : available approaches, critical limitations, and technical requirements / Peng Zhao and Meng-Xiang Sun. Zygote development and embryogenesis in angiosperms ; The MZT during early angiosperm embryogenesis ; Studies on the MZT during embryogeneis and technical limitations ; Current techniques used to study the MZT in higher plants ; Conclusions and perspectives