Computational biology of transcription factor binding /
General Material Designation
[Book]
First Statement of Responsibility
edited by Istvan Ladunga.
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
New York, NY :
Name of Publisher, Distributor, etc.
Humana Press,
Date of Publication, Distribution, etc.
c2010.
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
xi, 454 p. :
Other Physical Details
ill. ;
Dimensions
26 cm.
SERIES
Series Title
Methods in molecular biology,
Series Title
Springer protocols
Volume Designation
674
ISSN of Series
1064-3745 ;
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index.
CONTENTS NOTE
Text of Note
An overview of the computational analyses and discovery of transcription factor binding sites -- Components and mechanisms of regulation of gene expression -- Regulatory regions in DNA: promoters, enhancers, silencers, and insulators -- Three-dimensional structures of DNA-bound transcriptional regulators -- Identification of promoter regions and regulatory sites -- Motif discovery using expectation maximization and Gibbs' sampling -- Probabilistic approaches to transcription factor binding site prediction -- The motif tool assessment platform (MTAP) for sequence-based transcription factor binding site prediction tools -- Computational analysis of ChIP-seq data -- Probabilistic peak calling and controlling false discovery rate estimations in transcription factor binding site mapping from ChIP-seq -- Sequence analysis of chromatin immunoprecipitation data for transcription factors -- Inferring protein-DNA interaction parameters from SELEX experiments -- Kernel-based identification of regulatory modules -- Identification of transcription factor binding sites derived from transposable element sequences using ChIP-seq -- Target gene identification via nuclear receptor binding site prediction -- Computing chromosome conformation -- Large-scale identification and analysis of C-proteins -- Evolution of cis-regulatory sequences in drosophila -- Regulating the regulators: modulators of transcription factor activity -- Annotating the regulatory genome -- Computational identification of plant transcription factors and the construction of the plant TFDB database -- Practical computational methods for regulatory genomics: a cisGRN-lexicon and cisGRN-browser for gene regulatory networks -- Reconstructing transcriptional regulatory networks using three-way mutual information and bayesian networks -- Computational methods for analyzing dynamic regulatory networks.
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OTHER EDITION IN ANOTHER MEDIUM
Title
Computational biology of transcription factor binding.