Pt .4. Nanotechnologies for biomolecular delivery, gene therapy and expression control -- 33. Real-time imaging of gene delivery and expression with DNA nanoparticle technologies / Wenchao Sun and Assem G. Ziady-- 34. Nanoparticle-mediated gene delivery / Sha Jin, John C. Leach, and Kaiming Ye-- 35. Magnetic nanoparticles for local drug delivery using magnetic implants / Rodrigo Fernández-Pacheco, J. Gabriel Valdivia, and M. Ricardo Ibarra -- 36. Functionalized magnetic nanoparticles as an In Vivo delivery system / Shu Taira, Shinji Moritake, Takahiro Hatanaka, Yuko Ichiyanagi,and Mitsutoshi Setou -- 37. Formulation/preparation of functionalized nanoparticles for In Vivo targeted drug delivery / Frank Gu, Robert Langer, and Omid C. Farokhzad -- 38. Detection of mRNA in single living cells using AFM nanoprobes / Hironori Uehara, Atsushi Ikai, and Toshiya Osada -- 39. Reverse transfection using gold nanoparticles / Shigeru Yamada, Satoshi Fujita, Eiichiro Uchimura, Masato Miyake, and Jun Miyake -- 40. Custom-designed molecular scissors for site-specific manipulation of the plant and mammalian genomes / Karthikeyan Kandavelou and Srinivasan Chandrasegaran -- 41. Determining DNA sequence specificity of natural and artificial transcription factors by cognate site identifier analysis / Mary S. Ozers, Christopher L. Warren, and Aseem Z. Ansari
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Pt. 2. Technologies of physical science and chemistry in detection and analysis of biomolecules -- 11. Quantitative chemical analysis of single cells / Michael L. Heien and Andrew G. Ewing -- 12. Trapping and detection of single molecules in water / M. Willander, K. Risveden, B. Danielsson, and O. Nur -- 13. ZnO nanorods as an intracellular sensor for pH measurements / M. Willander and Safaa Al-Hilli -- 14. Analysis of biomolecules using surface plasmons / M. Willander and Safaa Al-Hilli -- 15. Use of residual dipolar couplings in structural analysis of protein-ligand complexes by solution NMR spectroscopy / Nitin U. Jain -- 16. Raman-assisted x-ray crystallography for the analysis of biomolecules / Dominique Bourgeois, Gergely Katona, Eve de Rosny, and Philippe Carpentier -- 17. Methods and software for diffuse x-ray scattering from protein crystals / Michael E. Wall -- 18. Deuterium labeling for neutron structure-function-dynamics analysis / Flora Meilleur, Kevin L. Weiss, and Dean A.A. Myles -- 19. Small-angle neutron scattering for molecular biology: basics and instrumentation / William T. Heller and Kenneth C. Littrell -- 20. Small-angle scattering and neutron contrast variation for studying bio-molecular complexes / Andrew E. Whitten and Jill Trewhella -- 21. Protein sequencing with tandem mass spectrometry / Assem G. Ziady and Michael Kinter -- 22. Metabolic analysis / Vladimir V. Tolstikov --
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Pt. 3. Applications of quantum dots and molecular fluorescence in detection, tracking and imaging of biomolecules -- 23. Multicolor detection of combed DNA molecules using quantum dots / Christophe Escudé, Bénédicte Géron-Landre, Aurélien Crut,and Pierre Desbiolles -- 24. Quantum dot molecular beacons for DNA detection / Nathaniel C. Cady -- 25. Quantum dot hybrid gel blotting: a technique for identifying quantum dot-protein/protein-protein interactions / Tania Q. Vu and Hong Yan Liu -- 26. In Vivo imaging of quantum dots / Isabelle Texier and Véronique Josserand -- 27. Semiconductor fluorescent quantum dots: efficient biolabels in cancer diagnostics / Patricia M. A. Farias, Beate S. Santos, and Adriana Fontes -- 28. Monitoring and affinity purification of proteins using dual tags with tetracysteine motifs / Richard J. Giannone, Yie Liu, and Yisong Wang-- 29. Use of genomic DNA as reference in DNA microarrays / Yunfeng Yang -- 30. Single-molecule imaging of fluorescent proteins expressed in living cells / Kayo Hibino, Michio Hiroshima, Masahiro Takahashi, and Yasushi Sako-- 31. MicroPET, microSPECT, and NIR fluorescence imaging of biomolecules In Vivo / Zi-Bo Li and Xiaoyuan Chen -- 32. Ultrahigh resolution imaging of biomolecules by fluorescence photoactivation localization microscopy / Samuel T. Hess, Travis J. Gould, Mudalige Gunewardene, Joerg Bewersdorf, and Michael D. Mason --
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Pt. I. Applications of microfluidics and nanopores in separation, detection, manipulation, and analysis of biomolecules -- 1. HPLC-Chip/MS technology in proteomic profiling / Martin Vollmer and Tom van de Goor-- 2. Nanofluidic channel fabrication and manipulation of DNA molecules / Kai-Ge Wang and Hanben Niu -- 3. A Single-molecule barcoding system using nanoslits for DNA analysis: nanocoding / Kyubong Jo, Timothy M. Schramm, and David C. Schwartz -- 4. Microfluidic devices with photodefinable pseudo-valves for protein separation / Z. Hugh Fan -- 5. Microfluidic chips designed for measuring biomolecules through a microbead-based quantum dot fluorescence assay / Kwang-Seok Yun, Dohoon Lee, Hak-Sung Kim, and Euisik Yoon -- 6. DNA focusing using microfabricated electrode arrays / Faisal A. Shaikh and Victor M. Ugaz -- 7. Solid-state nanopore for detecting individual biopolymers / Jiali Li and Jene A. Golovchenko-- 8. Inserting and manipulating DNA in a nanopore with optical tweezers / U. F. Keyser, J. van der Does, C. Dekker, and N. H. Dekker -- 9. Forming an a-hemolysin nanopore for single-molecule analysis / Nahid N. Jetha, Matthew Wiggin, and Andre Marziali -- 10. Nanopore force spectroscopy on DNA duplexes / Nahid N. Jetha, Matthew Wiggin, and Andre Marziali --