عنوان

Multiple sclerosis immunology :

(Number (ISBN

1461479533 (electronic bk.)

(Number (ISBN

9781461479536 (electronic bk.)

Erroneous ISBN

9781461479529

Number

b431295

Title Proper

Multiple sclerosis immunology :

General Material Designation

[Book]

Other Title Information

a foundation for current and future treatments /

First Statement of Responsibility

Takashi Yamamura, Bruno Gran, editors

Specific Material Designation and Extent of Item

1 online resource (xvii, 461 pages):

Other Physical Details

illustrations (some color)

Text of Note

Includes bibliographical references and index

Text of Note

Th17 cells in autoimmune inflammation and demyelination in the central nervous system -- Regulatory T cells in MS -- T-bet: A critical regulator of encephalitogenic T Cells -- Antigen-presenting cells in the Central Nervous System -- The role of B cells in multiple sclerosis -- Diet, gut flora and multiple sclerosis: current research and future perspectives -- GM-CSF in autoimmune inflammation of the central nervous system -- The role of Toll-like receptors in multiple sclerosis and experimental autoimmune encephalomyelitis -- Macrophages and microglia in experimental autoimmune encephalomyelitis and multiple sclerosis -- Genetics of multiple sclerosis -- Gene expression profiling and pathway analysis for identification of molecular targets in MS -- Systems biology for the study of multiple sclerosis -- Checkpoints in the development of pathogenic and regulatory T cells in Experimental Autoimmune Encephalomyelitisa basis for current future interventions in MS -- Modeling MS in non-human primates -- A novel concept of treatment in MS: targeting both oligodendrocyte death and inflammatory processes by inhibiting poly (ADP-Ribose) polymerase -- Association of MS with other autoimmune diseases -- Current and future treatments of Multiple Sclerosis -- Targeting CD52 for the treatment of Multiple Sclerosis -- Haematopoietic stem cells for the treatment of MS -- Mesenchymal stem cells for the treatment of Multiple Sclerosis

0

Text of Note

The availability of powerful genome-wide association study technology, during the last five years, has shown that most of the new MS susceptibility loci are immune-response genes. It is clear that there is much novelty in the field of MS immunology, which has served as an impetus to invest in new therapies. Notably, most if not all of these are immunotherapies. Even the equally exciting field of cell-based therapies and neuro-regeneration may well rely on cells or growth factors that are no less immunomodulators than restorative of myelin and neural cell function. Multiple Sclerosis Immunology looks at MS immunology as the basis for the present andeven morethe future of treatments for this complex autoimmune condition. Both editors are immunologists, as well as clinical neurologists, and appreciate the importance of a sustained dialogue between basic and clinical scientists to ensure that translation is real and not just virtual

Title

Multiple sclerosis immunology

International Standard Book Number

9781461479529

Title

OhioLINK electronic book center (Online)

Title

SpringerLink

Multiple sclerosis

Multiple sclerosis-- Immunological aspects

Multiple sclerosis-- Immunotherapy

HEA-- 039000

MED-- 014000

MED-- 022000

MED-- 045000

MED-- 112000

Number

Edition

Class number

Class number

Gran, Bruno

Yamamura, T., (Takashi)

Ohio Library and Information Network

Date of Transaction

20131202122227.0

Cataloguing Rules (Descriptive Conventions))

pn

Electronic name

[Book]

Y