Biotransformation and metabolite elucidation of xenobiotics /
General Material Designation
[Book]
First Statement of Responsibility
edited by Ala F. Nassar
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
Hoboken, N.J. :
Name of Publisher, Distributor, etc.
John Wiley & Sons,
Date of Publication, Distribution, etc.
c2010
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
xi, 328 p. :
Other Physical Details
ill. ;
Dimensions
25 cm
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index
CONTENTS NOTE
Text of Note
Human biotransformation / Andrew Parkinson ... [et al.] -- Analytical tools and approaches for metabolite identification in drug metabolism / Yongmei Li -- Tools of choice for accelerating metabolite identification : mass spectrometry technology drives metabolite identification studies forward / Ala F. Nassar -- Improving drug design : considerations for the structural modification process / Ala F. Nassar -- Case study : the unanticipated loss of N2 from novel DNA alkylating agent laromustine by collision-induced dissociation : novel rearrangements / Ala F. Nassar ... [et al.] -- Case study : identification of in vitro metabolite/decomposition products of the novel DNA alkylating agent laromustine / Ala F. Nassar ... [et al.] -- Strategies for the detection of reactive intermediates in drug discovery and development / Mark P. Grillo -- Safety testing of drug metabolites : MIST guidance impact on the practice of industrial drug metabolism / J. Greg Slatter