عنوان

Protein amyloid aggregation

(Number (ISBN

1493929771

(Number (ISBN

9781493929771

Erroneous ISBN

9781493929788

Number

b398347

Title Proper

Protein amyloid aggregation

General Material Designation

[Book]

Other Title Information

methods and protocols /

First Statement of Responsibility

edited by David Eliezer, Weill Cornell Medical College, New York, NY, USA.

Place of Publication, Distribution, etc.

Springer,

Name of Publisher, Distributor, etc.

Humana Press ;

Date of Publication, Distribution, etc.

[2015]

Series Title

Methods in molecular biology,

Series Title

Springer protocols,

Volume Designation

volume 1345

ISSN of Series

1064-3745 ;

ISSN of Series

1949-2448

Text of Note

Includes bibliographical references and index.

Text of Note

This detailed volume focuses on methods for the characterization of aggregation processes that lead to the formation of amyloid fibrils and amyloid oligomers which feature in the etiology of a variety of human disorders collectively known as amyloidoses. The scope of the collection includes techniques for visualizing early steps on the amyloid formation pathway, methods for capturing and characterizing oligomeric, potentially toxic, intermediates, strategies for preparing and characterizing mature amyloid fibrils, and approaches for understanding templating and transmission of amyloid aggregates. Written in the highly successful Methods in Molecular Biology series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Protein Amyloid Aggregation: Methods and Protocols serves as an ideal guide for biochemists and biophysicists with an interest in elucidating the mechanisms of protein amyloid formation, as well as chemists, pharmacologists, and clinicians with an interest in leveraging an understanding of such mechanisms for the purpose of therapeutic development.

Life sciences, Laboratory manuals.

Proteins, Laboratory manuals.

Amyloid.

Protein Aggregates.

Protein Aggregation, Pathological.

Eliezer, David.

Date of Transaction

20181223160836.0

Electronic name

[Book]

Y