عنوان

Stem cell bioprocessing :

(Number (ISBN

1907568883

(Number (ISBN

9781907568886

Number

b395089

Title Proper

Stem cell bioprocessing :

General Material Designation

[Book]

Other Title Information

for cellular therapy, diagnostics and drug development /

First Statement of Responsibility

Tiago G. Fernandes, Maria Margarida Diogo and Joaquim M.S. Cabral.

Specific Material Designation and Extent of Item

xviii, 217 pages :

Other Physical Details

illustrations ;

Dimensions

25 cm.

Series Title

Woodhead Publishing series in biomedicine ;

Volume Designation

number 40

Text of Note

Includes bibliographical references and index.

Text of Note

Stem cell bioprocessing describes the main large-scale bioprocessing strategies for both stem cell culture and purification, envisaging the application of these cells for regenerative medicine and drug screening. Bioreactor configurations are described, including their applications for stem cell expansion, and stem cell separation techniques such as isolation and purification are discussed. Basic definitions are provided concerning the different types of stem cells, from adult stem cells to the more recent induced pluripotent stem cells. The main characteristics of these different stem cell types are described, alongside the molecular mechanisms underlying their self-renewal and differentiation. The book also focuses on methodologies currently used for in vitro stem cell culture under static conditions, including the challenge of xeno-free culture conditions, as well as culture parameters that influence stem cell culture. Approaches for both stem cell culture and separation in micro-scale conditions are presented, including the use of cellular microarrays for high-throughput screening of the effect of both soluble and extracellular matrix molecules. A further section is dedicated to application of stem cells for regenerative medicine. --

Biotechnology-- Materials.

Stem cells.

Bioreactors.

Cell Culture Techniques.

Cell Separation.

Regenerative Medicine-- methods.

Stem Cells.

Biotechnology-- Materials.

Stem cells.

Number

Class number

Book number

Class number

Class number

Fernandes, Tiago G.

Cabral, Joaquim S.

Diogo, Maria Margarida

Date of Transaction

20151020133616.0

Cataloguing Rules (Descriptive Conventions))

rda

Electronic name

[Book]

Y