Protein surface recognition : approaches for the inhibition of protein-protein interactions for drug discovery
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
Chichester, West Sussex
Name of Publisher, Distributor, etc.
John Wiley & Sons
Date of Publication, Distribution, etc.
2011
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
xvi, 321 p. : ill. )some col.(
GENERAL NOTES
Text of Note
Includes bibliographical references and index
NOTES PERTAINING TO TITLE AND STATEMENT OF RESPONSIBILITY
Text of Note
editors, Ernest Giralt, Mark Peczuh, Xavier Salvatella
CONTENTS NOTE
Text of Note
The discovery and characterization of protein-protein interactions / C. Bertoncini, A. Higueruelo, and Xavi Salvatella -- Biophysics of protein-protein interactions / Irene Luque -- On the logic of natural product binding in protein-protein interactivity / James J. La Clair -- Interface peptide inhibitors of PPIs / Mark W. Peczuh, and Richard T. Desmond -- Inhibition of protein-protein interactions by peptide mimics / Jorge Becerril ... ]et al.[ -- Discovery of inhibitors of protein-protein interactions by screening chemical libraries / Carlos Garcia-Echeverria -- High-throughput methods of chemical synthesis applied to the preparation of inhibitors of protein-protein interactions / Annaliese K. Franz, Jared T. Shaw, and Yuchen Tang -- In silico screening / F.J. Luque, and Xavier Barril -- In vitro and in vivo screening : screening by nuclear magnetic resonance / Ernest Giralt -- In vitro and in vivo screening : methods of high throughput screening / Wenjiao Song and Qing Lin -- Case study : inhibitors of the MDM2-p35 protein-protein interaction / Sanjeev Shangary, Denzil Bernard, and Shaomeng Wang -- Case study : the discovery of potent LFA-1 antagonists / Tom Gadek