عنوان

Clostridium difficile :methods and protocols /edited by Peter Mullany and Adam P. Roberts.

(Number (ISBN

9781603273640 (alk. paper)

(Number (ISBN

1603273646 (alk. paper)

(Number (ISBN

9781603273657 (e-ISBN)

(Number (ISBN

1603273654 (e-ISBN)

Number

GBB022396

.Language of Text, Soundtrack etc

لاتين

Title Proper

Clostridium difficile :methods and protocols /edited by Peter Mullany and Adam P. Roberts.

Place of Publication, Distribution, etc.

New York :

Name of Publisher, Distributor, etc.

Humana Press,

Date of Publication, Distribution, etc.

c2010.

Specific Material Designation and Extent of Item

x, 241 p. :ill. ;26 cm.

Text of Note

مرجع به حساب نمي آيد

Text of Note

Includes bibliographical references and index.

Text of Note

Part I. Introduction to Clostridium Difficile and the Disease It Causes -- 1. Clostridium difficile : No Longer an Enigmatic Pathogen? / Adam P. Roberts and Peter Mullany -- 2. Clostridium difficile and the Disease It Causes / Torbjoجˆrn Noreجپn -- Part II. Isolation and Culture Techniques -- 3. Clostridium difficile Isolation and Culture Techniques / Mike Wren -- Part III. Methods for Typing and Epidemiological Studies -- 4. Molecular Typing Methods for Clostridium difficile : Pulsed-Field GelElectrophoresis and PCR Ribotyping / Sandra Janezic and Maja Rupnik -- 5. Clostridium difficile Toxinotyping / Maja Rupnik -- 6. Multilocus Sequence Typing for Clostridium difficile / Ludovic Lemeجپe and Jean-Louis Pons -- Part IV. Biochemistry of the Organism -- 7. Molecular Methods to Study Transcriptional Regulation of Clostridium difficile Toxin Genes / Ana Antunes and Bruno Dupuy -- 8. Dissecting the Cell Surface / Robert Fagan and Neil Fairweather -- 9. Human Intestinal Epithelial Response(s) to Clostridium difficile / Nazila V. Jafari, Elaine Allan, and Mona Bajaj-Elliott -- Part V. Genomics -- 10. Comparative Genome Analysis of Clostridium difficile Using DNA Microarrays / Richard Stabler, Lisa Dawson, and Brendan Wren -- Part VI. Development of Systems for Genetic Analysis of the Organism -- 11. ClosTron-Targeted Mutagenesis / John T. Heap, Stephen T. Cartman, Sarah A. Kuehne, Clare Cooksley, and Nigel P. Minton -- 12. Methods for Gene Cloning and Targeted Mutagenesis / Glen P.

Text of Note

"Clostridium difficile is a major nosocomial pathogen and has been shown to be a primary cause of antibiotic-associated disease. Recently, there has been an emergence of highly transmissible and frequently antibiotic-resistant strains, and the organism has become a considerable burden on health-care systems worldwide. At the same time, there has been a dramatic increase in our ability to study the organism. This book brings together the key workers in C. difficile research to describe the recently developed methods for studying the organism. These range from methods for isolation of the organism, molecular typing, genomics, genetic manipulation, and the use of animal models. We are now therefore in a position to gain an in-depth understanding of how this organism is transmitted and how it causes disease."--P. v.

Entry Element

Clostridium difficile--Research--Methodology.

Entry Element

Clostridium difficile

Entry Element

Bacteriological Techniques

Class number

Entry Element

مولف

Entry Element

Mullany, Peter,

Entry Element

Roberts, Adam P.

Dates

1959-