تعیین اثر داروی جینکو بیلوبا بر روی نقائص شناختی بیماران مبتلا به اسکیزوفرنیای بستری در بخشهای توانبخشی مرکز روانپزشکی رازی
[پایاننامه]
.Evaluation of Ginkgo Biloba effect on cognitive deficit in patients with schizophrenia in rehabilitation wards of Razi psychiatry center
علوم بهزیستی و توانبخشی university of social welfare and rehabilitation))
، ۱۳۹۰
۶۲ص.
پیوست
چاپی
دکترا
روانپزشکی psychiatry
۱۳۹۰/۱۲/۲۲
علوم بهزیستی و توانبخشی university of social welfare and rehabilitation))
Objective The objective of this study was to examine the effects of Ginkgo Biloba on cognitive of patients with schizophrenia in 5 domains: attention, language, visual memory, short- term memory and reasoning. Method 44 schizophrenia patients (DSM-IV-TR) who were hospitalized in Razi hospital and had stable mental state and without any general medical condition or history of seizure or other serious neurologic problems were divided in two equall groups by chance. Then one group was taken Ginkgo Biloba and the other one placebo in a double blind fashion. At beginning and at the end of study (12 weeks) the patients were assessed by NCSE (Neurobehavioral Cognitive Status Examination). The result were analyzed with t test. Results According to this study Ginkgo Biloba is relatively safe. No serious adverse effect were seen, although the cause of withdrawn in two patients were. However, significant drug effects on short- term memory, reasoning and understanding of language found in patients. Conclusion According to our study Ginkgo Biloba is both relatively safe and useful in schizophrenic patients so that can improve the function and quality of life of them by improving their cognitive deficits. Key words Schizophrenia, Ginkgo Biloba, Cognitive deficit, Neurobehavioral Cognitive Status Examination (NCSE).
ba
.Evaluation of Ginkgo Biloba effect on cognitive deficit in patients with schizophrenia in rehabilitation wards of Razi psychiatry center