Epigenetics has emerged recently as an important area of molecular biological studies. Epigenetic modifications lead to potentially heritable but reversible alterations in the expression of genes that determine cell fate. Epigenetic misregulation is thus often linked to degenerative diseases, cancer and neuronal disorders. Recent biomedical interest in this regulatory system stems from the fact that epigenetic, in contrast to genetic, alterations are in principle amenable to pharmacological intervention. A few epigenetically active drugs, for example histone deacetylase inhibitors (HDACi) and.
Pharmacogenetics
Neoplasms- genetics
Epigenesis, Genetic
Medicine
Pharmacy
Genetics, Medical
QV38
.
5
E64
2011
Gasser, Susan M
Li, En
ایران
QV38.5 E64 2011
Susan M. Gasser_ En Li Epigenetics and Disease Pharmaceutical Opportunities Progress in Drug Research_ Vol. 67 2010.pdf
عادی
محرمانه
Susan M. Gasser_ En Li Epigenetics and Disease Pharmaceutical Opportunities Progress in Drug Research_ Vol. 67 2010.pdf