/edited by Andrâe F. Carvalho, Department of Clinical Medicine and Translational Psychiatry Research Group, Faculty of Medicine, Federal University of Cearââa, Fortaleza, CE, Brazil, Roger S. McIntyre, Departments of Psychiatry and Pharmacology, Mood Disorders Psychopharmacology Unit, University of Toronto, Toronto, ON, Canada
First edition
xiv, 160 pages,
:illustrations ;20 cm
Oxford psychiatry library
Includes bibliographical references at the end of each chapters and index
1. Treatment-resistant major depressive disorder: current definitions, epidemiology, and assessment -- 2. Treatment-resistant bipolar disorder: current definitions, epidemiology, and assessment -- 3. Determinants of treatment resistance: health systems and public policy implications -- 4. The influence of psychiatric and medical comorbidities in treatment resistance for mood disorders -- 5. Predictors of treatment response in major depressive disorder -- 6. Predictors of treatment response in bipolar disorder: lessons from longitudinal studies -- 7. Evidence-based pharmacological approaches for treatment-resistant major depressive disorder -- 8. Evidence-based pharmacological approaches for treatment-resistant bipolar disorder -- 9. Psychosocial management of treatment resistant mood disorders: current evidence -- 10. Electroconvulsive therapy for treatment-resistant mood disorders: current evidence -- 11. Novel non-invasive brain stimulation approaches for treatment-resistant mood disorders -- 12. Vagus nerve stimulation and deep brain stimulation: implantable device-related neurostimulation for treatment-resistant mood disorders -- 13. Novel therapeutic targets for major depressive disorder -- 14. Novel therapeutic targets for bipolar disorder.