Computational methods for mass spectrometry proteomics
[Book]
/ Ingvar Eidhammer ... [et al.
Chichester, England ;Hoboken, NJ
: John Wiley & Sons
, 2007.
x, 284 p. , ill. , 25 cm.
Print
Includes bibliographical references (p. [265]-275) and index.
Protein, proteome, and proteomics -- Protein separation : 2D gel electrophoresis -- Protein digestion -- Peptide separation : HPLC -- Fundamentals of mass spectrometry -- Mass spectrometry : MALDI-TOF -- Protein identification and characterization by MS -- Tandem MS or MS/MS analysis -- Fragmentation models -- Identification and characterization by MS/MS -- Spectral comparisons -- Sequential comparison : de novo sequencing -- Database searching for de novo sequences -- Large-scale proteomics -- Quantitative MS-based proteomics -- Peptides to proteins -- Top-down proteomics -- Standards.