RNA interference : application to drug discovery and challenges to pharmaceutical development
Hoboken, N.J.
Wiley
1102c
xiv, 310 p. : ill.
Includes bibliographical references and index
edited by Paul H. Johnson
)Publisher-supplied data( RNA interference: What is it? / James A. Birchler -- Nucleic acids as regulatory molecules / Faqing Huang, CJ Yu, and Yanlin Guo -- Use of siRNA oligonucleotides to study gene function / Kristin A. Wiederholt and Adam N. Harris -- Genome scanning by RNA interference / Roderick L. Beijersbergen and Oliver C. Steinbach -- Discovery of new siRNA delivery agents / Paul H. Johnson, Diane Frank, Kunyuan Cui, Roger Adami, Harry Wang, Michael Houston, and Steven C. Quay -- In vivo Delivery of siRNA: challenges and strategies / Aliasger K. Salem and Mark A. Behlke -- Interferon, cytokine induction and other potential in vivo toxicities / Adam Judge, Marjorie Robbins, and Ian MacLachlan -- Application of RNA interference to viral diseases / Ralph A. Tripp and Stephen Mark Tompkins