عنوان

Development of a Monte Carlo Simulation Model for Varian ProBeam Compact Single-Room Proton Therapy System Using GEANT4

TL53210

انگلیسی

Development of a Monte Carlo Simulation Model for Varian ProBeam Compact Single-Room Proton Therapy System Using GEANT4

[Thesis]

String, Shawn

Muhammad, Wazir

Florida Atlantic University

2020

58 p.

M.S.

Florida Atlantic University

2020

Proton therapy with pencil beam scanning technique is a novel technique to treat cancer patients due to its unique biophysical properties. However, a small error in dose calculation may lead towards undesired greater uncertainties in planed doses. This project aims to create a simulation model of Varian ProBeam Compact using the GEANT4 Monte Carlo simulation tool kit. Experimental data from the first clinical ProBeam Compact system at South Florida Proton Therapy Institute was used to validate the simulation model. A comparison was made between the experimental and simulated Integrated Depth-Dose curves using a 2%/2mm gamma index test with 100% of points passing. The beam spot standard deviation sizes (_S) were compared using percent deviation. All simulated _S matched the experimental _S within 2.5%, except 70 and 80 MeV. The model can be used to develop a more comprehensive model as an independent dose verification tool and further investigate dose distribution.

Cancer therapies

Monte Carlo simulation

Physics

Protons

String, Shawn

Muhammad, Wazir

Florida Atlantic University

p

[Thesis]

276903

a

Y