عنوان

Hereditary breast cancer /

0849390222

9780849390227

b800171

Hereditary breast cancer /

[Book]

edited by Claudine Isaacs, Timothy R. Rebbeck.

New York :

Informa Healthcare,

©2008.

xiii, 384 pages :

illustrations ;

26 cm

Includes bibliographical references and index.

The genetic epidemiology of hereditary breast cancer / Douglas F. Easton, Antonis C. Antoniou, and Deborah Thompson -- Risk prediction in breast cancer / Lisa Walker and Rosalind Eeles -- Bioethics of genetic testing for hereditary breast cancer / Beth N. Peshkin and Wylie Burke -- Cancer risks in BRCA1 and BRCA2 mutation carriers / Kenneth Offit and Peter Thom -- PTEN and Cowden syndrome / Kevin M. Zbuk, Jennifer Stein, and Charis Eng -- Li-Fraumeni syndrome / Louise C. Strong -- Rare causes of inherited breast cancer susceptibility / Katherine L. Nathanson -- Low-penetrance genes in breast cancer / Paul D.P. Pharoah -- Biology of BRCA1- and BRCA2-associated carcinogenesis / Jenny Llamas and Lawrence C. Brody -- Genetic testing and counseling issues / Jill Stopfer, Vickie Venne, and Katherine Schneider -- Molecular diagnostics : methods and limitations / Sean V. Tavtigian and Florence LeCalvez-Kelm -- Breast cancer risk modifiers / Roger Milne and Georgia Chenevix-Trench -- BRCA1 and BRCA2 in underserved and special populations / Bifeng Zhang and Olufunmilayo I. Olopade -- Psychological and behavioral impact of BRCA1/2 genetic testing / Kristi Graves and Marc D. Schwartz -- Breast cancer screening and prevention options in BRCA1 and BRCA2 mutation carriers / Karen Lisa Smith and Claudine Isaacs -- Ovarian cancer screening and prevention options : ovarian cancer screening and its limitations. Who should be screened? / Karen H. Lu and Steven J. Skates -- Management of BRCA-negative hereditary breast cancer families / Noah D. Kauff -- Pathology of breast tumors in hereditary breast cancer / William D. Foulkes and Lars A. Akslen -- Pathology of ovarian tumors in mutation carriers / Frédérique Penault-Llorca and Sunil R. Lakhani -- Local treatment issues in women with hereditary breast cancer / Merav A. Ben-David and Lori J. Pierce -- Systemic therapy for BRCA-associated breast cancer / Mark Robson.

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Practically focusing on the needs of the medical oncologist, obstetrician, and gynecologist, this source analyzes the epidemiological, biological, and clinical issues associated with hereditary breast cancer, and offers clear guidance on the application and utilization of cancer risk assessment models, screening options for individuals with HBS, and the identification of high-risk patients. Addressing every essential aspect of HBC, this source offers succinct analyses of HBC-associated syndromes, low penetrance genes, and mutations of the BRCA 1 and BRCA 2 genes.

Breast-- Cancer-- Genetic aspects.

Breast Neoplasms-- genetics.

Genetic Predisposition to Disease.

Genetic Testing.

Breast-- Cancer-- Genetic aspects.

Isaacs, Claudine.

Rebbeck, Timothy R.

20201207123315.0

[Book]

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