Endothelial cell-leukocyte interactions during CNS inflammation / J. Steven Alexander and Alireza Minagar -- Interactions of the CNS and immune system / Monica J. Carson, Crystal S. Anglen, and Corinne Ploix -- Cytokines and brain : health and disease / Tammy Kielian and Paul D. Drew -- Chemokines and central nervous system disorders / William J. Karpus -- Circulating cell-derived microparticles in thrombotic and inflammatory disorders / Wenche Jy [and others] -- Multiple sclerosis : clinical features, immunopathogenesis, and clinical management / William A. Sheremata -- Neuroprotective effects of interferon-b in multiple sclerosis / Fabrizio Giuliani, Rana Zabad, and V. Wee Yong -- Acute disseminated encephalomyelitis / Sean J. Pittock and Dean M. Wingerchuk -- Ingested type interferon in experimental autoimmune encephalomyelitis / Staley A. Brod.
Neuromyelitis optica / Dean M. Wingerchuk -- Transverse myelitis : clinical manifestations, pathogenesis, and management / Douglas A. Kerr [and others] -- Optic neuritis : pathogenesis, immunology, and clinical management / Rohit Bakshi and Robert Zivadinov -- Central nervous system vasculitis : pathogenesis, immunology, and clinical management / Shariq Mumtaz [and others] -- Neurosarcoidosis : pathogenesis, immunology, and clinical management / Dakshinamurty Gullapalli and Lawrence H. Phillips II -- Neuropsychiatric SLE : pathogenesis, immunology, and clinical management / Deborah Aleman-Hoey and Robin Brey -- Gene expression in HIV-associated dementia / Paul Shapshak [and others] -- Human T-lymphotropic virus-associated neurological disorders : pathogenesis, immunology, and clinical treatment / Michael Lairmore [and others] -- West Nile virus infection of the nervous system : pathogenesis, immunology, and clinical management / Douglas J. Lanska.
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This is a cutting-edge review of the fundamental biological principles underlying the more common inflammatory disorders of the nervous system. The authors provide extensive updates on the latest findings concerning the mechanisms of inflammation and introduce such new concepts and methodologies as "endothelial and leukocyte microparticles" and "gene microarray technology" to help explain important links between the central nervous system (CNS) and general inflammatory processes. Among the diseases examined from an inflammatory perspective are multiple sclerosis, acute diss.