Machine derived contents note: 1 JCV and BKV: Mechanisms of Viral Transformation -- Toratore, C. (Washington, D.C.) -- 28 The Bovine PapillomavirusType-1 E5 Oncoprotein -- Goldstein, D.J. (Frederick, Md.); Sparkowski, J.J. (Wilmington, Del.) -- 44 The Action of E6 and E7 of Human Papillomaviruses in Cellular -- Immortalization and Transformation -- Hubert, W.G.; Laimins, L.A. (Chicago, Ill.) -- 64 HSV-2Transformation: A Multistep Process Mediated by Distinct -- Mutagenic DNA Sequences and Viral Genes Includes Activation -- of the Ras/MEK/MAPK Mitogenic Pathway -- Aurelian, L.; Smith, C.C. (Baltimore, Md.) -- 88 Transforming Genes of Human Cytomegalovirus and Human -- Herpesvirus 6 -- Muralidhar, S.; Rosenthal, L.J. (Washington, D.C.) -- 107 Transforming Genes of Human Herpesvirus 8 -- Rosenthal, L.J.; Muralidhar, S. (Washington, D.C.) -- 120 Transformation by the Epstein-BarrVirus -- Raab-Traub, N. (Chapel Hill, N.C.) -- 140 Oncogenic Transformation of T Cells by Herpesvirus saimiri -- Collins, C.M.; Medveczky, P.G. (Tampa, Fla.) -- 159 Subject Index.
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"Approximately 15% of human cancer incidence can be attributed to virus infection, i.e. viruses represent the second most important risk factor (after tobacco consumption) for cancer development in humans. Today, five virus types are known to be involved in causing human cancer: papillomaviruses, retroviruses, herpesviruses, hepadnaviruses, and flaviviruses." "This volume provides a comprehensive review of a number of DNA tumor viruses. Leading experts in the field of tumor virology discuss up-to-date information, focusing on the transforming genes of DNA tumor viruses, the mechanisms of transformation and the in vitro methodology used for their identification and characterization. In vitro studies have revealed several common mechanisms of viral transformation." "Presented in a clear and concise manner, this book will be of value to students as well as researchers in the fields of general biology, molecular biology, cell biology and microbiology."--BOOK JACKET.