New developments in integrated sample preparation for bioanalysis / M.W.J. van Hout, H.A.G. Niederländer, R.A. de Zeeuw and G.J. de Jong -- Solid-phase extraction on molecularly imprinted polymers / Lars I. Andersson and Leif Schweitz -- Techniques for sample preparation using solid-phase extraction / Uwe Dieter Neue, Claude R. Mallet, Ziling Lu, Yung-Fong Cheng and Jeffrey R. Mazzeo -- Turbulent flow chromatography in bioanalysis / Tony Edge -- Chiral bioanalysis / D.M. Wallworth and J.T. Lee -- Method development in reversed-phase chromatography / Uwe Dieter Neue, Eric S. Grumbach, Jeff R. Mazzeo, KimVan Tran and Diane M. Wagrowski-Diehl -- Immobilized enzyme reactors in liquid chromatography : on-line bioreactors for use in synthesis and drug discovery / Nektaria Markoglou and Irving W. Wainer -- Use of liquid chromatography-mass spectrometry in acute human toxicology / M.J. Bogusz -- HPLC-MS(MS) for bioanalysis in drug discovery and development / Brian Law -- Biomedical applications of directly-coupled chromatography : nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS) / John C. Lindon, Nigel J.C. Bailey, Jeremy K. Nicholson and Ian D. Wilson -- Ultra-sensitive detection of radiolabelled drugs and their metabolites using accelerator mass spectrometry / Graham Lappin and R. Colin Garner -- Biomedical applications of inductively coupled plasma mass spectrometry (ICP-MS) as an element specific detector for chromatographic separations / Fadi R. Abou-Shakra -- Chromatography in a regulated environment / H.M. Hill.
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Bioanalytical Separations is volume 4 of the multi-volume series, Handbook of Analytical Separations, providing reviews of analytical separation methods and techniques used for the determination of analytes across a whole range of applications. The theme for this volume is bioanalysis, in this case specifically meaning the analysis of drugs and their metabolites in biological fluids. - Discusses new developments in instrumentation and methods of analyzing drugs and their metabolites in biological fluids - Provides guidance to the different methods, their relative value to the user, and the advantages and pitfalls of their use - Future trends are identified, in terms of the potential impact of new technologies.
Elsevier Science & Technology
97327:97327
Bioanalytical separations.
9780444506580
Body fluids-- Analysis.
Drugs-- Analysis.
High performance liquid chromatography.
Body Fluids.
Chromatography-- methods.
Pharmaceutical Preparations-- analysis.
Spectrum Analysis-- methods.
Body fluids-- Analysis.
Drugs-- Analysis.
High performance liquid chromatography.
SCIENCE-- Chemistry-- Industrial & Technical.
TECHNOLOGY & ENGINEERING-- Chemical & Biochemical.