عنوان

Clinical trials in hypertension /

0824702700

9780824702700

b792799

Clinical trials in hypertension /

[Book]

edited by Henry R. Black.

New York :

Marcel Dekker,

©2001.

xi, 659 pages :

illustrations, maps ;

26 cm

Includes bibliographical references and index.

Department of Veterans Affairs Cooperative Study on Monotherapy of Hypertension -- The Systolic Hypertension in Europe Trial -- Hypertension Optimal Treatment (HOT) Study -- Beta-blocker Heart Attack Trial -- Effect of enalapril on morbid and mortal events among SOLVD participants with hypertension -- Captopril in Type 1 Diabetic Nephropathy -- Attenuation of ventricular enlargement: The SAVE study -- STOP-Hypertensio-2: The Swedish Trial in Old Patients with Hypertension-2 -- The Controlled ONset Verapamil INvestigation of Cardiovascular Endpoints (CONVINCE) Trial -- Rationale and design for the Antihypertensive and Lipid-lowering Treatment to Prevent Heart Attack Trial (ALLHAT) -- The 2nd Australian National Blood Pressure Study (ANBP2) --Losartan Intervention for Endpoint Reduction in Hypertension: The LIFE Study -- Prospective collaborative overviews of major randomized trials of blood-pressure-lowering treatments.

The Veterans Administration Cooperative Study on Antihypertensive Drugs -- The treatment of mild essential hypertension: The U.S. Public Health Service Hospitals Clinical Trial -- The Hypertension Detection and Follow-up Program -- The Australian National Blood Pressure Study 1973-1979 / Ralph Reader -- The MRC Trial of Treatment in Mild Hypertension -- Beta-blockers versus diuretics in hypertensive men: The HAPPHY Trial -- Metoprolol versus thiazide diuretics in hypertension: results from the MAPHY Study in perspective -- The European Working Party on High Blood Pressure in the Elderly (EWPHE) Trial -- The Swedish Trial in Old Patients with Hypertension (STOP-Hypertension) -- Systolic Hypertension in the Elderly Program (SHEP): the first demonstration that lowering systolic hypertension reduced total stroke and all coronary heart disease -- Medical Research Council Trial of Treatment of Hypertension in Older Adults -- The Treatment of Mild Hypertension Study (TOMHS): design and additional analyses.

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Compiling descriptions, results, and analyses from 24 complete or soon-to-be-complete influential clinical trials studying the efficacy of pharmacological therapy in hypertension, this detailed reference examines treatment for hypertension from a variety of perspectives, including trials sponsored by both international governments and pharmaceutical firms. Organized to facilitate convenient comparison and evaluation of results for therapeutic decisions, Clinical Trials in Hypertension: identifies objectives, inclusion/exclusion criteria, baseline characteristics of subjects, and drug regimens; spotlights trials that established the effectiveness of breakthrough treatments such as treating young hypertensives with diastolic blood pressure elevations; reviews numerous drug studies-including Heart Attack Primary Prevention in Hypertension (HAPPHY), Metoprolol Atherosclerosis Prevention in Hypertensives (MAPHY), and Treatment of Mild Hypertension Study (TOMHS)-contrasting diuretics, -adrenergic receptor blockers, angiotensin converting enzyme inhibitors, -adrenergic receptor blockers, and calcium antagonists; considers treatment options and results with older hypertensives; and more! Reports on the collaboration between the World Health Organization and the International Society of Hypertension pooling data from more than 30 clinical trials currently in progress.

Clinical trials-- Evaluation-- History.

Hypertension-- Chemotherapy-- Evaluation-- History.

Hypotensive agents-- Testing-- History.

Antihypertensive Agents-- therapeutic use.

Clinical Trials as Topic-- history.

Hypertension-- drug therapy.

Ätiologie

Clinical trials-- Evaluation.

Hypertonie

Hypotensive agents-- Testing.

Kontrollierte klinische Studie

Therapie.

Black, Henry R., (Henry Richard),1942-

20201207060216.0

[Book]

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