عنوان

Targeted therapies in oncology /

084939371X

9780849393716

b787328

Targeted therapies in oncology /

[Book]

edited by Giuseppe Giaccone, Jean-Charles Soria.

New York :

Informa Healthcare,

©2007.

ix, 412 pages :

illustrations ;

24 cm

Includes bibliographical references and index.

Overview of existing therapies / Jiannis Mountzios and Jean-Charles Soria -- Signal transduction inhibitors, HER family, EGFR inhibition, and clinical achievements / Giuseppe Giaccone and Paolo Zucali -- HER2 inhibition and clinical achievements / Toru Mukohara and Pasi A. Jänne -- Pan-HER inhibitors / Gérard Milano -- Inhibiting the phosphoinositide 3-kinase/Akt/mammalian target of rapamycin pathway / Janet E. Dancey -- Farnesyl transferase inhibitors in cancer: promise, but limited proof / Laura Fanucchi, Michael P. Fanucchi, and Fadlo R. Khuri -- Protein Kinase C inhibitors in the treatment of non-small cell lung cancer / Yun Oh [and others] -- Signal transduction inhibitors: PDGFR and c-KIT inhibitors / Jean-Yves Blay [and others] -- The insulin-like growth factor 1 receptor: a target for cancer treatment / Yungan Tao, Jean Bourhis, and Eric Deutsch -- Aurora kinase inhibitors / Mitesh J. Borad, Steven L. Warner, and Daniel D. von Hoff -- Apoptosis modulators: p53 targeting / Sunil Chada [and others] -- Survivin / Dario C. Altieri -- TRAIL modulators / C.H. Mom [and others] -- VEGF targeting / Lee M. Ellis -- Targeting angiogenesis with oral agents / Benjamin Besse and Jean-Pierre Armand -- Endothelial cell propagation targteing / Gordon C. Tucker -- HIF-1 inhibitors / Giovanni Melillo -- Antivascular agents / Jane Robertson -- Matrix metalloproteinases / Stéphane Vignot and Jean-Philippe Sapno -- Src inhibitors / Francisco Cruzalegui -- Telomerase and Telomere interacting agents / Jean-Franc̦oi Riou [and others] -- Targeting Hsp90: the cancer super-chaperone / Paul Workman and Swee Sharp.

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This book presents an authoritative overview of existing molecular targeted therapies, their relevance and role for specific tumors, and their clinical efficacy and impact on patient treatment.

Cancer-- Treatment.

Genetic Therapy.

Immunotherapy.

Neoplasms-- therapy.

Cancer-- Treatment.

Giaccone, Giuseppe.

Soria, Jean-Charles.

20201207010337.0

[Book]

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