Includes bibliographical references (pages 299-362) and index.
Eukaryotic transposable elements: teaching old genomes new tricks / Susan R. Wessler -- Immunoglobulin recombination signal sequences: somatic and evolutionary functions / Ellen Hsu -- Somatic evolution of antibody genes / Rupert Beale and Dagmar Iber -- Regulated and unregulated recombination of G-rich genomic regions / Nancy Maizels -- The role of the genome in the initiation of meiotic recombination / Rhona H. Borts and David T. Kirkpatrick -- Nuclear duality and the genesis of unusual genomes in ciliated protozoa / Carolyn L. Jahn -- Editing informational content of expressed DNA sequences and their transcripts / Harold C. Smith -- Alternative splicing: one gene, many products / Brenton R. Graveley -- Imprinting: the hidden genome / Alyson Ashe and Emma Whitelaw.
Sequence-dependent properties of DNA and their role in function / Donald M. Crothers -- Mutation as a phenotype / Errol C. Friedberg -- Repeats and variation in pathogen selection / Christopher D. Bayliss and E. Richard Moxon -- Tuning knobs in the genome: evolution of simple sequence repeats by indirect selection / David G. King, Edward N. Trifonov, and Yechezkel Kashi -- Implicit information in eukaryotic pathogens as the basis of antigenic variation / J. Dave Barry -- The role of repeat sequences in bacterial genetic adaptation to stress / Eduardo P.C. Rocha -- The role of mobile DNA in the evolution of prokaryotic genomes / Garry Myers, Ian Paulsen, and Claire Fraser.
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Discusses three interconnected themes: information can be implied, rather than explicit, in a genome; information can lead to focused and/or regulated changes in nucleotide sequences; and information that affects the probability of distinct classes of mutation has implications for evolutionary theory.