edited by Stella Pelengaris and Michael Khan ; with contributions from Maria Blasco [and others].
Malden, MA :
Blackwell Pub.,
2006.
1 online resource (x, 531 pages) :
illustrations
Includes bibliographical references and index.
Genetic instability, chromosomes and repair / Stella Pelengaris, Mike Khan -- Cancer is more than a genetic condition / Stella Pelengaris, Mike Khan -- Cell-matrix adhesion, cell-cell interactions and metastases / Charles Streuli -- Tumor immunity and immunotherapy / Cassian Yee -- Angiogenesis / David T. Shima, Christiana Ruhrberg -- Diagnosis of cancer / Anne Thomas, William Steward -- Treatment of cancer : chemotherapy and radiotherapy / A.L. Thomas, R.A. Sharma, W.P. Steward -- Caring for the cancer patient / Nicky Rudd, Esther Waterhouse -- Genomics and proteomics in cancer research and diagnosis / Norbert C.J. de Witt.
Introduction / Stella Pelengaris, Mike Khan -- The burden of cancer / William Steward, Anne Thomas -- Nature and nurture in oncogenesis / Stella Pelengaris, Mike Khan -- DNA replication and the cell cycle / Stella Pelengaris, Mike Khan -- Regulation of growth : growth factors, receptors and signaling pathways / Stella Pelengaris, Mike Khan -- Oncogenes / Stella Pelengaris, Mike Khan -- Tumour suppressor genes / Martine Roussel -- Apoptosis / Stella Pelengaris, Mike Khan -- Telomeres and senescence / Maria Blasco, Mike Khan.
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This comprehensive text provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. Written by an international panel of researchers, specialists and practitioners in the field, the text discusses all aspects of cancer biology from the causes, development and diagnosis through to the treatment of cancer.; Written by an international panel of researchers, specialists and practitioners in the field.; Covers both traditional areas of study and areas of controversy and emerging importance, highlighting future directions for research.; Features.